DNA Structure & Function

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Author:
jaguavai
ID:
110226
Filename:
DNA Structure & Function
Updated:
2011-10-19 12:19:44
Tags:
Roseman 2014 Pharm 411
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Description:
DNA stuff from Dr. Hanson
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  1. Nucleoside vs. Nucleotide
    • Nucleoside is base + ribose
    • Nucleotide is base + ribose + phosphates
  2. Pyrimidines
  3. Purines
  4. Chargraff's rule
    • Amount of A will always equal T
    • Amount of C will always equan G
  5. Histones
    • Order DNA into nucleosomes like beads on a string
    • Further organized into chromosomes`
  6. DNA ligase functions
    • Joining of Okazaki fragments
    • DNA Repair
  7. DNA repair mechanisms
    • Recognition of damage (lesion)
    • Removal (excision of damage)
    • Replace (fill the gap) using sister strand as a template
    • Ligation
  8. Steps of DNA synthesis
  9. Nucleotide bonding

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