-
Ephedrine
- Alpha-Adrenergic Drug
- Appetite suppressant
-
Epinephrine
- Alpha-Adrenergic Drug
- Beta 1 & 2 -Adrenergic Drug
- Anaphylaxis
-
Norepinephrine
- Alpha-Adrenergic Drug
- Neuro Transmitter
-
Pseudoephedrine
- Alpha-Adrenergic Drug
- Nasal Decongestant
-
Tetrahydrozoline
- Alpha-Adrenergic Drug
- Vasoconstrictor (contract BV)
-
Metaproterenol
- Beta 2 -Adrenergic Drug
- Bronchodilator
-
Albuterol
- Beta 2 -Adrenergic Drug
- Bronchodilator
-
Salmeterol
- Beta 2 - Adrenergic Drug
- Bronchodilator
-
Alpha-Adrenergic Drug
- sympathomimetics
- Contraction of smooth muscle
- Sympathetic NS
-
Beta-Adrenergic Drug
- Stimulation of Heart: Beta1
- Bronchodilation: Beta 2
- Sympathetic NS
-
Alpha-Adrenergic Blocking Drug
- Inhibit/ block Sympathetic activity --> Vasodilation, Lowering BP
- Treatment of Hypertension
- Sympathetic NS
-
Beta-Adrenergic Blocking Drug
- Selective: only works on Beta 1
- Non-selective: works both Beta 1&2
- Sympathetic NS
-
Doxazosin
- Alpha-Adrenergic Blocking Drug
- Decrease BP
-
Parazosin
- Alpha-Adrenergic Blocking Drug
- Benign Prostate Hypertrophy
-
Terazosin
- Alpha-Adrenergic Blocking Drug
- Benign Prostate Hypertrophy
-
Labetalol
- Non-selective Beta-Adrenergic Blocking Drug
- Hypertention
-
Propranolol
- Non-selective Beta-Adrenergic Blocking Drug
- Hypertension
-
Atenolol
- Selective Beta-1 Adrenergic Blocking Drug
- Hypertension
-
Metoprolol
- Selective Beta-1 Adrenergic Blocking Drug
- Hypertension
-
What is the receptor in Parasympathetic NS?
- Cholinergic Receptor - 3 types
- Muscarinic Receptors
- Nicotinic I Receptors
- Nicotinic II Receptors (this is in Somcati NS)
-
Cholinergic Drug
- Parathympathomimetic
- 2 types: Direct Acting Cholinergic Drug & Indirect acting Cholinergic Drug
-
Direct Acting Cholinergic Drug
- These drugs act like Acetylcholine (ACH)
- Bind to the Muscarinic receptors
- Stimulate the Parasympatheic NS
-
Indirect acting Cholinergic Drug
- These drugs inhibit Acetycholinesterase (enzyme to degrete ACH)
- As a result, increase of accumulate ACH
-
Anticholinergics
- Parasympathetic NS
- Compete against ACH --> prevent ACH to bind to the receptors
-
Acetylcholine (ACH)
- Direct-acting Cholinergic Drug
- Miotic in cataract surgery
-
Pilocarpine
- Direct-acting Cholinergic Drug
- Gluacoma
-
Bethanechol
- Direct-acting Cholinergic Drug
- Urinary retention
-
Pyridostigmine
- Indirect-acting Cholinergic Drug
- Myasthenia gravis
-
Ambenonium
- Indirect-acting Cholinergic Drug
- Myasthenia gravis
-
Edrophonium
- Indirect-acting Cholinergic Drug
- Myasthenia gravis
-
Atropine
- Anticholinergic Drug
- increase hear rate
-
Scopolamine
- Anticholinergic Drug
- Motion Sickness
-
Dicyclomine
- Anticholinergic Drug
- GI disorders such as Ulcers, Colitis
-
-
Ganglionic Blocker
- block both ACH and Nicotine
- interfere with both sympathetic and parasympathetic NS
- Decrease heart rate
- Increase vasodilation
-
Succinylcholine
- Depolarizing Blockers (Alters NicotinicII receptor)
- Somatic NS - Peripherally Acting Skeletal Muscle Relaxants
-
Tubocuramine
- Non-depolarizing Blocker (Competitive to ACH, so that ACH cannot bind to the Nicotinic II receptors)
- Somatic NS - Peripherally Acting Skeletal Muscle Relaxants
-
Metocurine
- Non-depolarizing Blocker (competitive to ACH)
- Somatic NS - Peripherally Acting Skeletal Muscle Relaxants
-
Pipecuronium
- Non-depolarizing Blocker (competitive to ACH)
- Somatic NS - Peripherally Acting Skeletal Muscle Relaxants
-
Dentrolene
- Direct Acting Skeletal Muscle Relaxants --> prevent the sckeletal muscle fibers from contracting
- Somatic NS - Peripherally Acting Skeletal Muscle Relaxants
- Only peripheralskeletal muscle relaxant given by PO (mouth)
-
Baclofen
- Centrally acting skeletal muscle relaxants (depressing the impulse conduction in spainal cord --> relax skeletal muscle
- Somatic NS - Centrally Acting Skeletal Muscle Relaxants
- Does NOT interfere with Nicotinic II reseptors or muscle fibers
-
Cyclobenzaprine
- Centrally acting skeletal muscle relaxants (depressing the impulse conduction in spinal cord to relax skeletal muscle
- Somatic NS - Centrally Acting Skeletal Muscle Relaxants
- Does NOT interfere with Nicotinic II receptors or muscle fibers
-
Methocarbamol
- Centrally acting skeletal muscle relaxant (depresses the impulse conduction to relax skeletal muscle)
- Somatic NS - Centrally Acting Skeletal Muscle Relaxants
- Do NOT interfere with Nicortinic II receptors or muscle fibers
-
Carisoprodol
- Somatic NS - Centrally acting skeletal muscle relaxant (depressed the impule conduction to relax skeletal muscle)
- Do NOT interfere with Nicotinic II receptors or muscle fibers
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