Exam 002 - FNP 3

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  1. Exenatide ?
    Brand name?
    Injection or PO?
    • Given this history, exenatide is sometimes referred to as "lizard spit".
    • Brand name: Byetta
    • Class: Incretin Mimetics
    • For DM-2
    • SubQ injection, must be Refrigerated at 36-46 F.
    • Found in the saliva of Gila Monster. It is like Glucagon-like peptide-1 (GLP-1) that regulates glucose metabolism and insuline secretion.
    • Theraputics: It enhences Glucose-dependent insuline secretion, lowers Glucagon secretion, and slows gastric emptying.
  2. Thia-zoli-dine-dione (TZD) ?
    S/E ?
    • Glitazone
    • Rosiglitazone (Avandia) --> Increased risk of CV events.
    • Pioglitazone (Actos) --> Increases risk of Bladder cancer.
    • Main S/E: Heart failure from Water-retention, edema, weight gain in up to 5% of patients.
  3. Bladder cancer Risk with which Glitazone ?
    • Actos (Pioglitazone)
    • Pneumonic:
    • An Actor having to pee a lot due to bladder cancer while she is on ACTOS to treat her DM-2.
    • Pio-Glitazone = Pee a lot.
  4. CV risk with which Glitazone ?
    • Rosi-glitazone (Avandia)
    • Pneumonic: Heart pierced by thorns of Rose plant.
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Exam 002 - FNP 3
Exam 002 - FNP 3
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