Rnur 131 Pharmacology 1

Home > Preview

The flashcards below were created by user dorothy on FreezingBlue Flashcards.


  1. Pharmacogenomics/Pharmacogenetics
    the sudy of genetically determined variations in the response to drugs
  2. Pharmacology
    study of the biological effects of chemicals
  3. Pharmacodynamics
    • the way a drug affects the body;
    • science dealing with interactions b/w the chemical compounds of living systems and the foreign chemicals, including drugs, that enter living organisms
  4. Pharmacokinetics
    the way a body deals with a drug, including absorption, distribution, biotransformation, excretion
  5. Pharmacokinetics:
    Critical Concentration
    the amount of drug that is needed to cause therapeutic effect
  6. Pharmacokinetics:
    Loading Dose
    higher dose than that usually used, at the start of treatment to reach critical concentration
  7. Pharmacokinetics:
    Absorption
    what happens to a drug from the time it enters the body until it enters the circulating fluid
  8. Pharmacokinetics:
    Routes of administration:
    • IV-fastest absorption
    • IM
    • subQ
    • PO
    • Mucous membrane
  9. Pharmacokinetics:
    Distribution
    involves movement of a drug to the body's tissues
  10. Pharmacokinetics:
    Blood Brain Barrier
    protective system of cellular activity that keeps many things away from the CNS; must be highly lipid soluble to reach the CNS
  11. Pharmacokinetics:
    Placenta & Breast Milk
    benefit must clearly outweigh the risks
  12. Pharmacokinetics:
    Biotransformation
    • Metabolism; the process by which drugs are changed into new, less active chemicals.
    • Everything absorbed in GI tract enters liver to be "treated"; then liver detoxifies many chemicals and uses others to produce needed enzymes and structures.
  13. Pharmacokinetics:
    Excretion
    • removal of a drug from the body
    • drugs that are water soluble are excreted thru kidneys via glomerular filtration
  14. Adverse Reactions:
    1. Primary
    2. Secondary
    3. Hypersensitivity
    • 1. Primary: enhanced desired effect
    • 2. Secondary: side effects
    • 3. Hypersensitivity: excessively responsive to primary or secondary effects
  15. Drug allergies:
    1. Anaphylaxis
    2. Cytotoxic
    3. Serum Sickness
    4. Delayed
    • 1. Anaphylaxis: ab's that can lead to respiratory distress or arrest
    • 2. Cytotoxic: ab's that circulate in the blood and attack antigens on cell sites
    • 3. Serum sickness: ab's that circulate in blood and cause damage to various tissues by depositing in blood vessels
    • 4. Delayed: ab's bound to specific white blood cells
  16. Image Upload
    • gentamicin (Garamycin)
    • neomycin (Mycifradin)
    • steptomycin
    • tobramycin (Tobrex)
  17. Image Upload
    • Ototoxicity
    • Renal toxicity
  18. Image Upload
    • Pregnancy & lactation
    • With aminoglycosides
    • NO alocohol use within 72 hours
  19. Image Upload
    • children (developing cartilage)
    • photosensitivity
  20. Image Upload
    • Lactation due to superinfex in babies
    • With tetracyclines
  21. Image Upload
    • TERATOGENIC
    • pregnancy & lactation
    • renal disease & kidney stones
    • CNS effects
    • rash
    • photosensitivity
  22. Image Upload
    • hepatoxicity
    • turns teeth gray
    • photosensitivity
    • oral contraceptives
    • superinfections
    • NO food or dairy
  23. Image Upload
    ceflacor (Ceclor)
  24. Image Upload
    ciprofloxacin (Cipro)
  25. Image Upload
    amoxicillin (Amoxil)
  26. Image Upload
    cotrimoxazole (Septra, Bactrim)
  27. Image Upload
    tetracycline
  28. Image Upload
    • amantadine (Symmetrel)
    • oseltamavir (Tamiflu)
    • acyclovir (Zovirax)
  29. Image Upload
    • fluconazole (Diflucan)
    • nystatin (Nilstat)
  30. Image Upload
    • clotrimazole (Lotrimin, Mycelex)
    • miconazole (Monistat)
    • terinafline (Lamisil)
    • toinaftate (Tinactin)
  31. Image Upload
    mebendazole (Vermox)

Card Set Information

Author:
dorothy
ID:
111373
Filename:
Rnur 131 Pharmacology 1
Updated:
2011-10-23 22:27:44
Tags:
Rnur 131
Folders:

Description:
Pharmacology 1
Show Answers:

Home > Flashcards > Print Preview