Pharm Exam 3: HTN drugs

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Author:
Anonymous
ID:
111696
Filename:
Pharm Exam 3: HTN drugs
Updated:
2011-10-24 06:03:58
Tags:
hypertension renin aldosterone angiotensinogen angiotensin nI ACE inhibitors Ca channel blockers beta
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Description:
Drugs to treat HTN
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  1. Renin
    • Enzyme which catalyzes conversion of angiotensinogen to angiotensin I
    • Release is triggered by: decline in BP, decline blood volume, decline in plasma Na+ conc, and decline in renal perfusionn pressure
  2. ACE (angiotensin-converting enzyme)
    • Enzyme which catalyzes conversion of Angiotensin I (inactive form) to Angiotensin II (active form)
    • Located on luminal surfaces of all blood vessels
    • Vasculature of lungs rich in ACE
  3. Regulation of blood pressure by the Renin-Angiotensin-Aldosterone system

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