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2011-10-28 13:40:40
Lymphatic System

Lymphatic System
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  1. List the functions of the lymphatic system and the immune system?
    • a. transports protein from interstial space > blood
    • b. transports fat from sm. intestine > blood
    • c. resistance: ability to remain unaffected by noxious agents
  2. Define lymphoid organ?
    lymphocytes (immunity)
  3. List the lymphoid organs and their functions?
    • a. thymus- T cells mature here
    • b. spleen- filters blood
    • c. lymph nodes- filters lymph
  4. List the lymphoid locations?
    • a. thymus- mediastinum > deep to sternum
    • b. spleen- LUQ > between stomach and diaphragm
    • c. lymph nodes- along lymphocytes
  5. Define resistance?
    ability to remain unaffected by noxious agents
  6. Define nonspecific resistance?
    general fact (protect against any pathogen)
  7. Define specific resistance?
    destruction of specific target
  8. List the factors that contribute to nonspecific resistance?
    • a. physical barriers: skin cavity lining
    • b. mechanical factors: body fluids, resp. celia, peristalsis
    • c. chemical factors:
    • 1. Ph (skin, genetital tract, stomach)
    • 2. interferon- protein produced by virus infected cells (protect uninfected cells)
    • d. inflammation: tissue reaction to injury
  9. Define inflammation and identify its purpose?
    • tissue reaction d/t injury
    • destroys, dilutes, contains injurious agents and paves way for repair
  10. Define antigen?
    (Ag) molecule that causes an immune response
  11. Define antibody?
    (Ab) molecule produced in response to an Ag, combines with and destroys the Ag containing structure
  12. List the immune system cells and provide their functions?
    • a. macrophage: phagocytizes, processes, and presents Ag on its surface
    • b. B lymphocyte:
    • 1. plasma cell
    • 2. memory
    • c. T lymphocyte:
    • 1. cytotoxic- kills virus infected cells
    • 2. suppressor
    • 3. helper
    • 4. memory
  13. Outline the 2 types of cell interactions involved in immune response regulation?
    • a. indirect: via interleukins
    • b. direct:
    • 1. foreign antigen
    • 2. human leukocyte antigen
  14. Identify what mediates hemoral immunity?
    • immunoglobins
    • 1. IgM
    • 2. IgG
    • 3. IgA
  15. Identify what mediates cell mediated immunity (CMI)?
    cytotoxic T cells
  16. Define immunoglobulin?
  17. Characterize IgM, IgG, IgA?
    • IgM : first in blood
    • IgG: second in blood > #1 type > crosses placenta
    • IgA: secretions
  18. Contrast the primary and secondary responses regarding onset, duration, and intensity?
    • primary: first
    • secondary: d/t memory > faster onset, more intense, longer
  19. The secondary response is the result of what immune system characteristic?
  20. Define naturally acquired?
    d/t natural events
  21. Define naturally passive?
    • subject's immune system doesn't participate
    • ex: transfer of material Ab via breastmilk or placenta to child
  22. Define naturally active?
    • subject's immune system responds to normal Ag exposure
    • ex: cold virus immunity d/t past exposure
  23. Define artificially acquired?
    d/t medecine
  24. Define artificially passive?
    • administration of pre-formed Ab
    • ex: after HAV exposure to taco bell
  25. Define artificially active?
    • subject's immune system responds to admin. of Ag
    • ex: vaccines (HAV, measles, influenza)