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KHW
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Within the glomerulus, what structures allow small molecules & water to pass?
Podocytes
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Within the glomerulus, what structures regulate filtration via relaxation/constriction to alter SA
Mesengial Cells
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What induces constriction/contraction of mesengial cells?
- Sympathetic Innervation
- Angiotensin II
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Where is 60-70% of Na and H2O reabsorbed?
Proximal Convoluted Tubule
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What is permeable within the Descending Loop of Henle? Ascending Loop?
- Descending= H2O
- Ascending= Na & Cl
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What two drugs prolong Penn?
- Probenicide
- Sulphinpyrazone
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What Drugs act on the Proximal Tubule?
- Carboanhydrase Inhibitors:
- Acetazolamine
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What Drugs act on the Loop of Henle?
- Loop Diuretics:
- Furosemide
- Bumetadine
- Torasemide
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Which Drugs act on the Distal Convoluted Tubule?
- Thiazide Diuretics:
- Chlorothizide
- Hydrochlorothiazide
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What Drugs act on the Distal Convoluted Tubule?
- K Sparing Diuretics:
- Amilorida
- Triamterene
- Spironolactone
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Which class is a mild diurectic and used to Tx glaucoma?
Carboanhydrase Inhib
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Which drug type decreases the secretion of Uric Acid?
Loop Diuretics
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Which Class is the most powerful of all diruectics?
Loop Diuretics
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Which durg classes => Metabolic Acidosis?
Carboanhydrase Inhibitors
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Which drugs decreases Na reabsorption and H2O Reabsorption?
Osmotic Diuretics
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Which drug class is used to Tx Hypokalemia & edema/Ascites?
Distal/K Sparing Diuretics
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Which Drugs Classes => Metabolic Alkalosis?
- Loop Diuretics
- Thiazide Diuretics
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Which drugs => Hypokalemia?
Loop Diruetics
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Which durg may reduce bone loss?
Thiazides
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Which drug can cause hyperglycemia?
Thiazide
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Thiazides are used to Tx:
- Diabetes Insip.
- Mild HF
- Hypertension (Volume and Dilation)
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_______ will not be absorbed form horse urine
Weak Acids
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Amiloride is a _____ diuretic
K Sparing
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Action of Furosimide
Blocks Na-K-Cl CARRIER/SYMPORT
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Two vasodilators that affect renal perfusion:
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Thiazide Diuretics acts on….
The Distal Convoluted Tubule
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How & Where are Weak Acids excreted?
- Active Transporters in the
- Proximal Tubles
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Which Drugs increase renal perfusion? Which are Contraindicated w/ NSAIDS?
- Eicoasnoids (<- contraindicated)
- Thiazides
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