Diabetes therapy- Dental Therapeutics.txt

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Author:
Anonymous
ID:
113258
Filename:
Diabetes therapy- Dental Therapeutics.txt
Updated:
2011-10-30 20:24:13
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Diabetes Therapy Baker
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Description:
Baker Test #2 Dental Therapeutics
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  1. What are the types of oral antidiabetic drugs?
    • -thiazilidinediones
    • - biguanides
    • -sulfonylureas
    • -meglitinides
    • -Alpha glucosidase inhibitors
  2. What drugs sensitize the body to insulin and or control hepatic glucose production
    • Thiazolindendiones
    • Biguanides--> metformin
  3. What drugs stimulate the pancreas to make more insulin
    • Sulfonylureas
    • Meglitinides
  4. What drugs slow absorption of starches?
    Alpha glucosidase inhibitors
  5. Do biguanides decrease blood glucose levels?
    No they do not
  6. Do sulfanylureas decrease blood glucose levels?
    Yes they can cause HYPOGLYCEMIA
  7. Meglitinides main mechanism of action is
    Decrease post Prandial glucose levels
  8. What are the adverse effects thiazolidinediones?
    • -weight gain and edema
    • - hypoglycemia
    • - contribdicatednin patients with
    • --abnormal liver function and CHF
  9. What are the adverse effects of the biguanides?
    • Diarrhea and abdominal discomfort
    • - lactic acidosis if improperly prescribed
    • - LDL cholesterol decrease
    • Contraindicated with inpaired renal function
  10. What are the adverse effects of the sulfonylureas?
    • -hypoglycemia
    • - weight gain
  11. What are the adverse effects of meglitinides?
    • -hypoglycemia
    • -weight gain
  12. What are the adverse effects of alpha glucosidase inhibitors
    • -flatulence
    • -abdominal discomfort
    • Contraindicated in patients Witt cirrhosis and inflammatory bowel disease
  13. What is the criteria for diagnosis of diabetes post Prandial?
    • Normal= < 140 mg/dl
    • Impaired=140-199 mg/dl
    • Diabetes= 200 or more
  14. What is the criteria for diagnosing diabetes fasting glucose level
    • Normal = <110 mg/ dl
    • Impaired = 110-125 mg/ dl
    • Diabetes >= 126 mg/dl
  15. What is the significance of hbA1C?
    Describes average blood glucose over the last 2-3 months

    • - target range is 6.5 or below
    • - do not treat if 8 or over equivalent to 205 mg/ dl
  16. How many times should hba1c be taken per yr
    • 2 times if not on insulin
    • 4 times if takin insulin
  17. How do you manage type I diabetics clinically?
    • - morning appointments
    • - if NPO skip morning insulin
    • - do not resume normal insulin until normal caloric intake established
    • - have glucose source available
    • - aggressively treat oral infections
    • - routine post procedural antibiotics are inappropriate
  18. How do you manage type II diabetics in the clinical setting for minor procedures
    • W LA
    • - use usual medication if blood glucose is controlled

    W sedation

    - NPO for 8 hrs and withhold AM medications and long term medications the evening before, resumed after surgery
  19. How do you manage type II diabetics for moderate procedures?
    • - oral medication withheld the evening before
    • - NPO for 8 hrs
    • - long acting sulfonylureas converted to short acting agents a few days in advance
    • - metformin on discontinued 48 hrs before
    • - check blood glucose insulin may be required
    • - all poorly controlled diabetics reschedule
  20. How do you manage type II diabetics undergoing major surgery?
    • - modify and hold mess like moderate procedure
    • - treat with insulin like type I diabetics
    • - hospitalization for surgery may be needed
    • - treat type II diabetics on insulin like you treat type I

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