Vitamins

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Author:
bhugo85
ID:
113472
Filename:
Vitamins
Updated:
2011-10-31 18:22:31
Tags:
Med Vits
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Description:
Vitamins
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  1. Vit A - Fx
    • Antioxidant
    • Visual pigment
  2. Vit A - Deficiency
    • Night blindness
    • Dry skin
  3. Vit A - Excess
    • Headache/Hepatomegaly
    • Allopecia/Anorexia
    • Really painful bones
    • Dry skin/Drowsiness
  4. Vit B1
    Thiamine
  5. Vit B1 - Fx
    • PDH
    • αKDH
    • Transketolase - key to test for in Thiamine deficiency
  6. Vit B1 - Deficiency
    Beri Beri (alcoholics)
  7. Vit B2
    Riboflavin
  8. Vit B2 - Fx
    cofactor in redox
  9. Vit B2 - Deficiency
    • Cheliosis
    • Corneal vascularization
  10. Vit B3
    Niacin
  11. B3 - Fx
    constituent of NAD+ & NADP+
  12. B3 - Deficiency
    • Pellagra ("DDD")
    • Diarrhea
    • Dementia
    • Dermatitis
    • **Death
  13. Vit B5
    Pantothenate
  14. B5 - Fx
    component of CoA syn. to form acetyl CoA for metabolic pathways
  15. B5 - Deficiency
    • Dermatitis
    • Enteritis
  16. Vit B6
    Pyridoxine
  17. B6 - Fx
    used in transamination (detox of NH3) & decarboxylations
  18. B6 Deficiency
    • Convulsions
    • Peripheral neuropathy
  19. Vit B12
    Cobalamin
  20. B12 - Fx
    cofactor of homocysteine methyltransferase & methylmalonyl CoA mutase
  21. Homocysteine methyltransferase
    Releases stored folate
  22. Methylmalonyl CoA Mutase
    Source of succinyl CoA (substitue for acetyl CoA in TCA)
  23. B12 - Deficiency
    macrocytic / megaloblastic anemia
  24. Vit B9
    Folate
  25. B9 - Fx
    • converterd to THF
    • synthesis of DNA & RNA
  26. B9 - Deficiency
    macrocytic / megaloblastic anemia
  27. Biotin - Fx
    • cofactor for caroylation enzymes
    • (i.e. FA synthesis; acetyl coA to FA)
  28. Biotin - Deficiency
    Maculosquamous Dermatitis (MCD)
  29. Vit C - Fx
    • - Fe2+ absorption (keeps in Fe2+ state)
    • - Used for Hydroylases in collagen syn.
  30. Vit C - Deficiency
    Scurvy - decreased collagen type III (mesoderm)
  31. Vit D - Fx
    • absorbs Ca2+
    • increase bone reabsorption
  32. Vit D - Deficiency
    • Rickets (kids)
    • Osteomalacia (adults)
  33. Vit E - Fx
    protects erythrocytes from ROS damage
  34. Vit E - Deficiency
    • - Hemolytic anemia
    • - Neurodysfunction
  35. Vit K - Fx
    • catalyzes γ carboxylation
    • of glutamic residues on clotting proteins
  36. Vit K - Deficiency
    • - neonatal hemorrhage w/↑PT and PTT but normal
    • bleeding time

    - (-) by Warfarin

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