chap 18 251 micro

broad spectrum disease in any tissue as an abscess formation

implants have an increased chance of being inv=fected biofilms

30percent colonization in nares and invasion thru healthy nasal mucosa or skin

toxins and enzymes

• coagulase-fibrin clot:
• hyaluronidase-disolves tissue cement staphlokinase-disolves clots lipase-colonize oily areas of skin digesting lipids

• leukocidin-kills leukocytes panton valentine leukocidin-destroys alveoli
• hemolysins-kills many cells including rbcs
• scalded skin syndrome toxin: exfoliate
• toxic shock syndrom toxin:multi organ system failure enterotoxin: emetic toxin
• golden pigment: inhibits superoxide radicals in neutophil traps
• staplococcal protein a: inactivates igG

tss,respritory infections,would infection,imperigo,focal skin infections(carbuncle,furuncle(boil),cellilitis),endocarditis,food poisoning

person to person

can be nosocomial and community pathogen and drug resistant

• skin infections:drain wound or debride
• antibiotic;sensitivity tests
• mrsa use;vancomycin,linezolid,daptomycin,other