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nadiaessaqi
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staphylococcus aureus
broad spectrum disease in any tissue as an abscess formation
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staphylococcus aureus increased infection in
implants have an increased chance of being inv=fected biofilms
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staphylococcus aureus colonization and invasion
30percent colonization in nares and invasion thru healthy nasal mucosa or skin
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s.aureus use what
toxins and enzymes
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how does enzymes help s.aureus spread?
- coagulase-fibrin clot:
- hyaluronidase-disolves tissue cement staphlokinase-disolves clots lipase-colonize oily areas of skin digesting lipids
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toxins of s.aureus are what?
- leukocidin-kills leukocytes panton valentine leukocidin-destroys alveoli
- hemolysins-kills many cells including rbcs
- scalded skin syndrome toxin: exfoliate
- toxic shock syndrom toxin:multi organ system failure enterotoxin: emetic toxin
- golden pigment: inhibits superoxide radicals in neutophil traps
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s.aureus diseases
tss,respritory infections,would infection,imperigo,focal skin infections(carbuncle,furuncle(boil),cellilitis),endocarditis,food poisoning
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s.aureus transmission
person to person
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s.aureus unique characteristics
can be nosocomial and community pathogen and drug resistant
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treatment for s.aureus
- skin infections:drain wound or debride
- antibiotic;sensitivity tests
- mrsa use;vancomycin,linezolid,daptomycin,other
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