Chapter 11

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Author:
lisa0615
ID:
114636
Filename:
Chapter 11
Updated:
2011-11-05 13:09:32
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Vocabulary
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Vocabulary
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  1. when two different molecules associate or attach to each other
    complexation
  2. an abnormal sensitivity generally resulting in an allergic reaction
    hypersensitivity
  3. a potentially fatal hypersensitivity reaction producing severe respiratory distress and cardiovascular collapse
    anaphylactic shock
  4. an unexpected reaction the first time a drug is taken, generally due to genetic causes
    idiosyncasy
  5. the ability of a substance to cause cancer
    carcinogenicity
  6. when two drugs with similar pharmacological actions result in an effect equal to the sum of the individual effects
    synergism
  7. when two drugs with similar pharmacological actions produce greater effects than the sum of the individual effects
    additive effects
  8. a drug that antagonizes the toxic effect of another drug
    antidote
  9. a chronic and potentially fatal liver disease causing loss of function and increased resistance to blood flow through the liver
    cirrhosis
  10. an inflammation condition of the liver caused by viruses
    acute viral hepatitis
  11. when elements of ingested nutrients interact with a drug and this affects the disposition of the drug
    drug-diet interactions
  12. an obstruction of the bile duct that causes hepatic waste products and bile to accumulate in the liver
    obstructive jaundice
  13. a condition in which thyroid hormone secretions are above normal, often referred to as an overactive thyroid
    hyperthyroidism
  14. a condition in which thyroid secretions are below normal, often referred to as an underactive thyroid
    hypothyroidism
  15. a field of study which defines the hereditary basis of individual differeces in ADME processes
    pharmacogenetics
  16. an unintended side effect of a medication that is negative or in some way injurious to the patient's health
    adverse drug reaction
  17. an effect produced when one drug with no inherent activity of its own increased the activity of another drug
    potentiation
  18. a drug bound to a plasma protein is removed when another drug of greater binding potential binds to the same protein
    displacement
  19. the decrease in hepatic enzyme activity that results in reduced metabolism of drugs
    enzyme inhibition
  20. the increase in hepatic enzyme activity that results in greater metabolism of drugs
    enzyme induction

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