Respiratory Viruses

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Author:
ehamm
ID:
114718
Filename:
Respiratory Viruses
Updated:
2011-11-05 18:50:46
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Respiratory Viruses
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Description:
Resp. Viruses
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  1. Influenza
    • Orthomyxovirus - Segmented RNA
    • A and B major human strains
    • Pathogenesis: replicates in upper respiratory tract, cell mediated reaction causes destruction
    • Incubation: 1 - 2 days
    • Symptoms: Dry cough, fever, headache, myalgia, muscle ache, chills
    • resolves in a week, fatigue continues for several weeks
    • Complications: Baterial superinfection (Strep, H. Inf, Staph), Reynaud's, Guillan-Barre
    • Dx: Anti-hemagglutination
    • Tx: Ostelmavir
    • Prevention: Flumist, influenza vaccine (anti-H)
  2. Parainfluenza
    • Paramyxovirus (-) RNA Envelope
    • H, N, F
    • Three types
    • 1. Acute Croup in young kids
    • 2. Croupin small kids
    • 3. Bronchitis/Pneumonia < 1
    • 4. URI in older kids
    • Dx: Clinical, serology, isolation
    • Tx: Supportive
  3. RSV
    • Paramyxovirus - RNA (-)
    • G, F
    • Major cause of bronchiolitis in young kids
    • Starts in URT -> LRT
    • Kids with Th2 response have worst outsome
    • Poor immunity for repeat infections
    • Sx: Cought, wheezem respiratory distress 1-3 weeks
    • dx: IF
    • Tx: Supportive, ribavirin
    • Prevention: Anti-F Ab
  4. Adenovirus
    • Adenovirus - DS DNA, Naked
    • Persists in host for years - subclinical and latent
    • Febrile illness of childhood
    • Symtoms: Phayrngiconjuctival fever, pertusis like cough, conjunctivitis, cystitis, gastroenteritis
    • Dx: Isolate virus
    • Tx: supportive
    • Prevention: enteric coated live vaccine
  5. Common cold viruses
    • Rhino virus
    • Corona virus
    • Reovirus
    • Sx: no fever, sneezing, congestion, short duration 2-4 days

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