Quiz 7 - Phar 605

Card Set Information

Author:
VASUpharm14
ID:
115068
Filename:
Quiz 7 - Phar 605
Updated:
2011-11-06 23:59:09
Tags:
im too cool
Folders:

Description:
Top 121-140
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user VASUpharm14 on FreezingBlue Flashcards. What would you like to do?


  1. Loestrin FE
    generic?
    norethindrone, ethinyl estradiol, and ferrous fumarate/iron
  2. Loestrin FE
    class?
    oral contraceptive
  3. Loestrin FE
    MOA?
    suppression of luteinizing hormone (LH) and follicle stimulation hormone (FSH) result in the inhibition of ovulation. Thickening of the cervical mucous (inhibiting sperm penetration) and alteration of the endometrium (which inhibits implantation) might also contribute to the effectiveness of oral contraceptives.
  4. Loestrin FE
    dosage form?
    Tablets
  5. Microgestin FE
    generic?
    norethindrone, ethinyl estradiol, and ferrous fumarate/iron
  6. Microgestin FE
    class?
    oral contraceptive
  7. Microgestin FE
    MOA?
    suppression of luteinizing hormone (LH) and follicle stimulation hormone (FSH) result in the inhibition of ovulation. Thickening of the cervical mucous (inhibiting sperm penetration) and alteration of the endometrium (which inhibits implantation) might also contribute to the effectiveness of oral contraceptives.
  8. Microgestin FE
    dosage form?
    Tablets
  9. Junel FE
    generic?
    norethindrone, ethinyl estradiol, and ferrous fumarate/iron
  10. Junel FE
    class?
    oral contraceptive
  11. Junel FE
    MOA?
    suppression of luteinizing hormone (LH) and follicle stimulation hormone (FSH) result in the inhibition of ovulation. Thickening of the cervical mucous (inhibitng sperm penetration) and alteration of the endometrium (which inhibits implantation) might also contribute to the effectiveness of oral contraceptives.
  12. Junel FE
    dosage form?
    Tablets
  13. Lotensin
    generic?
    benazepril hydrochloride
  14. Lotensin
    class?
    antihypertensive
  15. Lotensin
    MOA?
    thought to be due to its suppression of the renin-angiotensin-aldosterone system by competitively inhibiting the angiotensin-converting enzyme (ACE). ACE converts angiotensin I to angiotensin II, one of the most potent vasoconstrictors known. Inhibition of ACE decreases plasma angiotensin II which leads to decreased aldosterone secretion. The latter may cause an increase in serum potassium. The net result is a decrease in peripheral resistance.
  16. Lotensin
    dosage form?
    Tablets
  17. Duragesic
    generic?
    fentanyl (transdermal)
  18. Duragesic
    class?
    opioid analgesic
  19. Duragesic
    MOA?
    analgesia is produced centrally via action on the central opiate receptors. Fentanyl interacts predominantly with opioid u-receptor.
  20. Duragesic
    dosage form?
    Transdermal systems (patches)
  21. Macrodantin
    generic?
    nitrofurantoin
  22. Macrodantin
    class?
    antibacterial
  23. Macrodantin
    MOA?
    may be due to an inhibition of acetyl-coenzyme A, interfering with the metabolism of carbohydrates in susceptible bacteria.
  24. Macrodantin
    dosage form?
    Capsules
  25. Macrobid
    generic?
    nitrofurantoin
  26. Macrobid
    class?
    antibacterial
  27. Macrobid
    MOA?
    may be due to an inhibition of acetyl-coenzyme A, interfering with the metabolism of carbohydrates in susceptible bacteria.
  28. Macrobid
    dosage form?
    Capsules
  29. Furadantin
    generic?
    nitrofurantoin
  30. Furadantin
    class?
    antibacterial
  31. Furadantin
    MOA?
    may be due to an inhibition of acetyl-coenzyme A, interfering with the metabolism of carbohydrates in susceptible bacteria.
  32. Furadantin
    dosage form?
    Suspension (25 mg/5 mL)
  33. Loestrin 24 FE
    generic?
    norethindrone acetate, ethinyl estradiol, and ferrous fumarate
  34. Loestrin 24 FE
    class?
    oral contraceptives
  35. Loestrin 24 FE
    MOA?
    Norethindrone is a progestogen and ethinyl estradiol is an estrogen. Absorption of both components from the GI tract is rapid with maximum plasma concentrations occurring 1 to 4 hours postdose. Norethindrone undergoes reduction and conjugation while ethinyl estradiol undergoes oxidation and conjugation. Oral contraceptives cuase suppression of luteinizing hormone (LH) and follicle stimulation hormone (FSH) resulting in the inhibition of ovulation. Thickening of the cervical mucous (inhibiting sperm penetration) and alteration of the endometrium (which inhibits implantation) may also contribute to their effectiveness.
  36. Loestrin 24 FE
    dosage form?
    Tablets (28 blister card)
  37. Tri-Cyclen-Lo
    generic?
    norgestimate and ethinyl estradiol
  38. Tri-Cyclen-Lo
    class?
    oral contraceptive
  39. Tri-Cyclen-Lo
    MOA?
    suppression of luteinizing hormone (LH) and follicle stimulation hormone (FSH) result in the inhibition of ovulation. Thickening of the cervical mucous (inhibiting sperm penetration) and alteration of the endometrium (which inhibits implantation) may also contribute to their effectiveness.
  40. Tri-Cyclen-Lo
    dosage form?
    Tablets (Ortho Tri-Cyclen Lo)
  41. Lanoxin
    generic?
    digoxin
  42. Lanoxin
    class?
    inotropic agent
  43. Lanoxin
    MOA?
    digitalis glycosides inhibit membrane bound Na+/K+ ATPase resulting in an increased intracellular Na+ concentration and a slightly decreased intracellular K+ concentration. The increased intracellular Na+ leads to an influx of extracellular Ca2+. The net result is an increase in the force and velocity of systolic contractions, a slowing of the heart rate, and a decreased conduction velocity through the AV node.
  44. Lanoxin
    dosage form?
    • Tablets
    • Elixir Pediatric
  45. Digitek
    generic?
    digoxin
  46. Digitek
    class?
    inotropic agent
  47. Digitek
    MOA?
    digitalis glycosides inhibit membrane bound Na+/K+ ATPase resulting in an increased intracellular Na+ concentration and a slightly decreased intracellular K+ concentration. The increased intracellular Na+ leads to an influx of extracellular Ca2+. The net result is an increase in the force and velocity of systolic contractions, a slowing of the heart rate, and a decreased conduction velocity through the AV node.
  48. Digitek
    dosage form?
    • Tablets
    • Elixir Pediatric
  49. Flovent
    generic?
    fluticasone propionate (inhalation)
  50. Flovent
    class?
    antiasthmatic
  51. Flovent
    MOA?
    adrenocorticoids bind to certain receptor proteins found in the cytoplasm of sensitive cells to form a steroid-receptor complex. The steroid-receptor complex enters the nucleus of the cell where it reacts with chromatin, or DNA. The steroid (or possibly the receptor) then uses stored information to stimulate, or in some cases inhibit, the transcription of m-RNA. The stimulation of m-RNA results in the synthesis of specific proteins and ultimately specific enzymes that carry out its antiallergy and anti-inflammatory actions.
  52. Flovent
    dosage form?
    inhalation aerosol in a metered dose inhaler (MDI)
  53. Keppra
    generic?
    levetiracetam
  54. Keppra
    class?
    anticonvulsant
  55. Keppra
    MOA?
    precise MOA is unknown. It is a pyrolidine derivative and is chemically unrelated to existing antiepileptic drugs. In animal models, it protects against pilocarpine and kainic acid-induced secondary generalized activity from focal seizures. It also inhibits burst firing in the hippocampus without affecting normal neuronal excitability. This may prevent propagation of seizure activity.
  56. Keppra
    dosage form?
    • Tablet (IR, ER)
    • Oral solution (IR)
  57. Hytrin
    generic?
    terazosin hydrochloride
  58. Hytrin
    class?
    antihypertensive
  59. Hytrin
    MOA?
    decreases total peripheral resistance by competitively blocking alpha-1-adrenoreceptors. This action results in dilation of arterioles and veins which leads to decreased blood pressure. Diastolic pressure is affected more than systolic pressure. In the treatment of benign prostatic hyperplasia, terazosin relaxes smooth muscle in the bladder neck and prostate, resulting in improvements in urine flow rates.
  60. Hytrin
    dosage form?
    Capsules
  61. Zovirax
    generic?
    acyclovir
  62. Zovirax
    class?
    antiviral
  63. Zovirax
    MOA?
    synthetic acyclic purine nucleotide which in vitro inhibits Herpes simplex types 1 and 2, varicella-zoster, Epstein-Barr, and cytomegalovirus. In vitro, the inhibitory activity of acyclovir is highly selective for Herpes simplex virus. Acyclovir is preferentially taken up and converted to the active triphosphate form by HSV infected cells which then interferes with the HSV DNA polymerase and inhibits viral DNA replication. In vitro, as the acyclovir triphosphate is incorporated into the growing chains of DNA by viral and cellular DNA polymerase, the DNA chain is terminated.
  64. Zovirax
    dosage form?
    • Tablets
    • Capsules
    • Ointment
    • Cream
    • Suspension
    • Powder for Injection
  65. Avapro
    generic?
    irbesartan
  66. Avapro
    class?
    antihypertensive
  67. Avapro
    MOA?
    angiotensin II is a potent vasoconstrictor, the primary vasoactive hormone of the renin-angiotensin system and an important component in the pathophysiology of hypertension. It also stimulates aldosterone secretion by the adrenal cortex. Irbesartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor found in many tissues. Irbesartan does not inhibit ACE or bind to or block other hormone receptors or ion channels known to be important in cardiovascular regulation.
  68. Avapro
    dosage form?
    Tablets
  69. Pulmicort
    generic?
    budesonide (inhalation)
  70. Pulmicort
    class?
    antiasthmatic
  71. Pulmicort
    MOA?
    adrenocorticoids bind to certain receptor proteins found in the cytoplasm of sensitive cells to form a steroid-receptor complex. The steroid-receptor complex enters the nucleus of the cell where it reacts with chromatin, or DNA. The steroid (or possibly the receptor) then uses stored information to stimulate, or in some cases inhibit, the transcription of m-RNA. The stimulation of m-RNA results in the synthesis of specific proteins and ultimately specific enzymes that carry out its antiallergy and anti-inflammatory actions. Budesonide has strong glucocorticoid and weak mineralcorticoid activity.
  72. Pulmicort
    dosage form?
    • Suspension for Inhalation
    • Metered Dose Inhaler (Flexhaler)
  73. Valtrex
    generic?
    valacyclovir hydrochloride
  74. Valtrex
    class?
    antiviral
  75. Valtrex
    MOA?
    Valacyclovir is rapidly converted to acyclovir by first-pass intestinal and/or hepatic metabolism. Acyclovir is a synthetic acyclic purine nucleotide which in vitro inhibits Herpes simplex types 1 and 2, varicella-zoster, Epstein-Barr, and cytomegalovirus. In vitro, the inhibitory activity of acyclovir is highly selective for Herpes simplex virus (HSV). Acyclovir is preferentially taken up and converted to the active triphosphate form by HSV infected cells which then interferes with the HSV DNA polymerase and inhibits viral DNA replication. In vitro, as the acyclovir triphosphate is incorporated into the growing chains of DNA by viral and cellular DNA polymerase, the DNA chain is terminated.
  76. Valtrex
    dosage form?
    Tablets
  77. Pristiq
    generic?
    desvenlafaxine
  78. Pristiq
    class?
    antidepressant
  79. Pristiq
    MOA?
    Non-clinical studies have shown that desvenlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake.
  80. Pristiq
    dosage form?
    Tablets (Extended-release)
  81. Tegretol
    generic?
    carbamazepine
  82. Tegretol
    class?
    anticonvulsant
  83. Tegretol
    MOA?
    appears to act by reducing polysynaptic responses and blocking the post-tetanic potentiation.
  84. Tegretol
    dosage form?
    • Tablets (chewable, oral)
    • Suspension
  85. Tegretol XR
    generic?
    carbamazepine
  86. Tegretol XR
    class?
    anticonvulsant
  87. Tegretol XR
    MOA?
    appears to act by reducing polysynaptic responses and blocking the post-tetanic potentiation.
  88. Tegretol XR
    dosage form?
    Tablets (Extended-Release)
  89. Carbatrol ER
    generic?
    carbamazepine
  90. Carbatrol ER
    class?
    anticonvulsant
  91. Carbatrol ER
    MOA?
    appears to act by reducing polysynaptic responses and blocking the post-tetanic potentiation.
  92. Carbatrol ER
    dosage form?
    Capsules (Extended-release)
  93. Equetrol ER
    generic?
    carbamazepine
  94. Equetrol ER
    class?
    anticonvulsant
  95. Equetrol ER
    MOA?
    appears to act by reducing polysynaptic responses and blocking the post-tetanic potentiation.
  96. Equetrol ER
    dosage form?
    Capsules (Extended-release)
  97. Alesse
    generic?
    levonorgestrel with ethinyl estradiol
  98. Alesse
    class?
    oral contraceptive
  99. Alesse
    MOA?
    suppression of luteinizing hormone (LH) and follicle stimulation hormone (FSH) result in the inhibition of ovulation. Thickening of the cervical mucous (inhibiting sperm penetration) and alteraction of the endometrium (which inhibits implantation) may also contribute to their effectiveness.
  100. Alesse
    dosage form?
    Tablets, 28 day pack
  101. Aviane
    generic?
    levonorgestrel with ethinyl estradiol
  102. Aviane
    class?
    oral contraceptive
  103. Aviane
    MOA?
    suppression of luteinizing hormone (LH) and follicle stimulation hormone (FSH) result in the inhibition of ovulation. Thickening of the cervical mucous (inhibiting sperm penetration) and alteration of the endometrium (which inhibits implantation) may also contribute to their effectiveness.
  104. Aviane
    dosage form?
    Tablets, 28 day pack
  105. Lithonate
    generic?
    lithium carbonate
  106. Lithonate
    class?
    antipsychotic
  107. Lithonate
    MOA?
    exact MOA of lithium in the treatment of mania is unknown. Its mood-stabilizing effects may be due to an antagonism of the release of norepinephrine and dopamine from nerve terminals or from increasing the reuptake and inactivation of catecholamines. Lithium does not inhibit the release of serotonin. Another potential mechanism of action is through depletion of phosphatidylinositides in selected cells in the CNS. This may decrease the responsiveness of neurons to various neurotransmitters.
  108. Lithonate
    dosage form?
    • Tablets (regular, sustained-release)
    • Capsules
    • Oral solution
  109. Lithotabs
    generic?
    lithium carbonate
  110. Lithotabs
    class?
    antipsychotic
  111. Lithotabs
    MOA?
    exact MOA of lithium in the treatment of mania is unknown. Its mood-stabilizing effects may be due to an antagonism of the release of norepinephrine and dopamine from nerve terminals or from increasing the reuptake and inactivation of catecholamines. Lithium does not inhibit the release of serotonin. Another potential mechanism of action is through depletion of phosphatidylinositides in selected cells in the CNS. This may decrease the responsiveness of neurons to various neurotransmitters.
  112. Lithotabs
    dosage form?
    • Tablets (regular, sustained-release)
    • Capsules
    • Oral solution
  113. Lithobid
    generic?
    lithium carbonate
  114. Lithobid
    class?
    antipsychotic
  115. Lithobid
    MOA?
    exact MOA of lithium in the treatment of mania is unkown. Its mood-stabilizing effects may be due to an antagonism of the release of norepinephrine and dopamine from nerve terminals or from increasing the reuptake and inactivation of catecholamines. Lithium does not inhibit the release of serotonin. Another potential mechanism of action is through depletion of phosphatidylinositides in selected cells in the CNS. This may decrease the responsiveness of neurons to various neurotransmitters.
  116. Lithobid
    dosage form?
    • Tablets (regular, sustained-release)
    • Capsules
    • Oral solution
  117. NuvaRing
    generic?
    etonogestrel and ethinyl estradiol (vaginal)
  118. NuvaRing
    class?
    contraceptive
  119. NuvaRing
    MOA?
    combination estrogen and progestin contraceptives cause suppression of luteinizing hormone (LH) and follicle stimulation hormone (FSH) resulting in the inhibition of ovulation. Thickening of the cervical mucous (inhibiting sperm penetration) and alteration of the endometrium (which inhibits implantation) may also contribute to their effectiveness. Etonogrestrel is the progestin component of Nuvaring and is the primary active metabolite produced following oral administration of desogestrel.
  120. NuvaRing
    dosage form?
    vaginal ring
  121. Mevacor
    generic?
    lovastatin
  122. Mevacor
    class?
    antihyperlipidemic
  123. Mevacor
    MOA?
    after oral ingestion, lovastatin is hydrolyzed to its beta-hydroxyacid form, becoming a specific inhibitor of HMG-CoA reductase. This enzyme is responsible for the conversion of HMG-CoA to mevalonate, an early rate limiting step in the synthesis of cholesterol. In therapeutic concentrations, HMG-CoA reductase is not completely blocked, allowing biologically necessary amounts of mevalonate to be produced. Mevacor reduces both normal and elevated LDL (low density lipoprotein) concentrations and VLDL (very low density lipoprotein) concentrations. It is not known whether Mevacor's therapeutic effect is due to an increased LDL catabolism, a decrease in VLDL (a precursor to LDL), or a direct decrease in LDL production. In addition to LDL reduction, Mevacor increases HDL (high density lipoprotein) concentrations. High LDL and low HDL levels have been shown to be risk factors in coronary heart disease.
  124. Mevacor
    dosage form?
    Tablets

What would you like to do?

Home > Flashcards > Print Preview