pharm3

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Author:
macco3
ID:
116544
Filename:
pharm3
Updated:
2011-11-13 20:25:17
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p3
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p3
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  1. When to schedule meds with antacids?
    One hour before or two hours after
  2. Antacids decrease absorption of which drugs
    • sucralfate
    • digoxin
    • ketoconazole
    • tetracycline
    • quinolone abx
  3. Population in need of high vitamin usage:
    • rapid body growth
    • pregnant/breastfeeding
    • malnoursihed
    • debilitated
  4. How and when to admin H2 blockers?
    • With meals
    • bedtime dose
    • rapid IV (<2min)= cardiac dysrthy, hypotension
  5. Prevpac contains?
    • Lansoprazole (PPI) (1)
    • amoxicillin (2)
    • clarithromycin (1)
    • BID morning, evening
  6. With prevpac, observe for?
    • anaphylaxis, rash, or serum sickness like rxn
    • signs of suprainfxn (candidiasis, c.diff)
    • chk fecal occult, H/H
  7. Antacids that contain __ cause diarrhea
    • Mg
    • caution use in pt with ostomy, hemorrhoid, ulcerative colitis, diverticulitis
  8. Antacids that contain___ cause constipation
    • Al, Ca
    • caution use in pt w/ hx of constipation, hemorrhoid
  9. When to admin cholestryamine?
    • Before meals
    • Incr fluids: 2500mL
    • Admin other drugs 1 hour before or 4-6 hours after
    • Sprinkle powder on liquid/semiliquid
  10. Cholestryamine DDI
    • HMG CoA reductase inhib
    • decreases warfarin (chk INR)
    • digoxin
    • corticosteroids
    • decreases absorption of propranolol, thiazide diuretics
  11. Lovastatin Adverse effects
    • rhabdomyolysis
    • myopathy
    • acute kidney failure
    • CATEGORY X
  12. Lovastatin DDI
    • Grapefruit
    • antacids dec. statin
    • incr digoxin
    • horme contraceptive
  13. Lovastatin--Monitor for
    • LFT
    • dc if transaminase 3xs normal
    • myositis
  14. When is Lovastatin taken?
    taken without regard to meals but must be taken consistently
  15. When to admin omeprazole?
    • immed. before meals, preferrably morning
    • with antacid to decrease GI distress
  16. Omeprazole DDI
    Increases warfarin, inc INR
  17. Sucralfate DDI
    • decreases warfarin
    • digoxin
    • theophylline

    Do NOT use with antacid, H2blocker, PPI
  18. How to admin sucralfate?
    • with water 1 hour before meal and at bedtime
    • taken on empty stomach

    via NG=bezoar
  19. Sucralfate--monitor for
    • constipation/diarrhea
    • used in caution for pt w/ renal failure
  20. Cimetidine DDI
    • Inc warfarine
    • amodarone
    • CCB
    • theophylline
  21. Cimetidine SE
    • constipation
    • confusion
    • dry mouth
    • problem in older pt w/ renal insuff
    • breast swelling/pain
    • Rare: neutropenia, tachycardia, agranulocytosis
  22. Misoprostol indications
    • prevention of NSAID induced gastric ulcer
    • off label: chronic constipation, early pregnancy termination
  23. Misoprostol SE
    • Pregnancy Category X
    • Black Box warning
    • stomach distress, diarrhea
  24. Misoprostol ok with antacids except for
    Mg containing antacids (diarrhea)
  25. When to admin misoprostol?
    With or after meals
  26. Gemfibrozil DDI
    • Hmg CoA increases rhabdomyolysis
    • incr anticoag effect w/ warfarin

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