Immunology: Streptococcal Infections

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Immunology: Streptococcal Infections
2011-11-14 11:27:12
Immunology Streptococcal Infections

Immunology: Streptococcal Infections
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  1. Streptococcus pyogenes is the most common causative agent of all the following disorders and complications except:
  2. All the following charachteristics are descriptive of M protein except:
    No known biologic role
  3. Substances produced by S. pyogenes include all the following except:
  4. Laboratory diagnosis of S. pyogenes can be made by all the following except:
    Febrile agglutinins
  5. False ASO results may be caused by all the following except::
    Room temperature reagents and specimens at the time of testing
  6. Members of the S. pyogenes species are almost always _____________ hemolytic.
  7. Long-term complications of S. pyogenes infection can include:
    Acute rheumatic fever and Post-streptococcal glomerulonephritis
  8. Particularly virulent serotypes of S. pyogenes produce proteolytic enzymes that cause ______________ in the wound or lesions on an extremity.
    necrotizing faciitis
  9. Describe Hyaluronidase produced by group A Streptococci.
    Also called "spreading factor"
  10. Describe Streptokinase produced by group A Streptococci.
    Dissolves clots by converting plasminogen to plasmin
  11. Describe Erythrogenic toxin produced by group A Streptococci.
    Responsible for characteristic scarlet fever rash
  12. Describe characteristics of S. Pyogenes:
    • It occures most frequestly in school-age children
    • It is spread by contact with large droplets produced in the upper respiratory tract.
    • It has been known to cause food-borne and milk borne epidemics.
  13. The clinical manifestations of S. Pyogenes associated upper respiratory infection are:
    Age dependent
  14. The most reliable immunologic test for recent S.pyogenes skin infections is:
    Anti-DNA B
  15. What occurs in the increase in severity of infection?
    Rising titer
  16. What occurs in the trend toward recovery?
    Declining titer
  17. What is not a current infection, but indicates a past infection?
    Constant (low) titer
  18. If a streptococcal infection is suspected, but the ASO titer does not exceed the reference range, a(n) _______________ should be performed.
    anti-DNAse B
  19. The classic tests to demonstrates the presence of streptococcal infection are:
    ASO and anti-DNAase B
  20. The highest reported levels of sensitivity testing for group A streptococci are in:
    Surface (optical) immunoassay