Ketogenesis

The flashcards below were created by user jaguavai on FreezingBlue Flashcards.

  1. Process
    Image Upload 1
  2. Step 1
    • 2 x acetyl CoA to acetoacetyl-CoA using thiolase
    • reversal of final step of beta oxidation
  3. Step 2
    • Acetoacetyl-CoA to HMG-CoA through HMG-CoA synthase.
    • Requires additional Acethyl-CoA and H20
  4. Step 3
    • HMG CoA to Acetoacetate through HMG-CoA lyase
    • Produces acetyl-CoA
  5. Step 4
    • Acetoacetate to acetone through acetoacetate decarboxylase (removal of CO2)
    • OR Acetoacetate to Beta hydroxybutyrate through beta-hydroxybutyrate dehydrogenase (NAD -> NADH)
  6. Ketone bodies as fuel
    Image Upload 2
Author
ID
117346
Card Set
Ketogenesis
Description
Ketogenesis steps etc.
Updated
Show Answers