Cholesterol Synthesis

Card Set Information

Author:
jaguavai
ID:
117380
Filename:
Cholesterol Synthesis
Updated:
2011-11-16 20:26:22
Tags:
Pharm 412 Roseman 2014
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Description:
Cholesterol Synthesis
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  1. Stages of cholesterol synthesis (4)
    • 1) condensation
    • 2) Conversion
    • 3) Polymerization
    • 4) Cyclization
  2. Step 1 (condensation)
    Of three acetate units to form the six-carbon intermediate mevalonate
  3. Step 2 (Conversation)
    of mevalonate to activated isoprene units
  4. Step 3 (Polymerization)
    of six five-carbon isoprene units to form squalene
  5. Step 4 (Cyclization)
    of squalene to form the four rings of the steroid nucleus
  6. Condensation
  7. Conversion
  8. Polymerization
  9. Cyclization

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