Relapsing Fever

Card Set Information

Author:
ehamm
ID:
117712
Filename:
Relapsing Fever
Updated:
2011-11-18 12:46:08
Tags:
Relapsing Fever
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Description:
Relapsing Fever
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  1. Organism
    • Gram negative
    • Stain with giemsa/wright stain
    • Microaerophilic
    • Abundent outer membrance proteins
    • Recombination possible for OMPs
  2. Epidemiology
    • Tick borne
    • Rabbit, bird, lizard reservoirs
    • Night feeding
    • Louse borne: must be crushed to pass on bacteria
  3. Pathogenesis
    • Symptoms with bacteremia
    • Endotoxin like features
    • Between episodes organism disappears
    • OMPs Ag different with each relapse
    • Immunity: humoral, lysis with complement
  4. Manifestations
    • One week incubations
    • high fever, rigors, severe headache, muscle pains, weakness
    • Last one week, abruptly ends
    • Relapses in 2-4 days
    • 1-4 relapses
    • Louse borne more fatal
  5. Diagnosis and Tx
    • Giemsa/wright staining
    • Presence among red cells
    • tetracycline

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