Ch30 Hematologic System

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Ch30 Hematologic System
2011-11-18 14:35:36

Hematologic System Ch30
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  1. RBC's lifespan is 120 days
  2. Reticulocyte is an immature erythrocyte
    the count measures the rate at which new RBC's appear in the circulation. They mature within 48hrs. of release into circulation.
  3. Neutrophil
    Primary phagocytic cells involved in acute inflammatory responses.
  4. Monocytes
    are the second type of WBC's to arrive at the scene of an injury.
  5. Platelets
    Have a lifespan of 5-9 days. They are the "Plugs" to close any openings in the capillary walls.
  6. Transferrin
    the degree to which transferrin is saturated with iron is a reliable indicator iof the iron supply for the developing RBC's.
  7. Thrombin converts fibrinogen to fibrin, which is an essential component of blood clot.
  8. 4 Major Functions of The Spleen
    • Hematopoietic-ability to produce RBC's fetal development
    • Filtration-ability to remove old & defective RBC's from circulation & recycle iron to the bone marrow
    • Immunologic-supply of lymphocytes, monocytes, & stored immunoglobulins.
    • Storage function- stores RBC's & platelets.
  9. Lymph System
    returns excess interstitial fluid to the blood which prevents edema.
  10. Assessment
    • ask what meds are being taken (herbal)
    • any surgeries (duodenum where iron is absorbed Vit B12)
    • any tumors (chemotherapy)
    • HIV(may cause depression to bone marrow)
    • Blood transfussions
    • Healing progression
  11. Sickle Cell occurs primarily in African Americans
  12. Pernicious anemia occurs most commonly in persons of northern European descent
  13. Hematemesis (bright red, brown, black vomitus)
    can be a symptom of chronic alcohol abusers. It damage platelet & liver function where cloting factors are produced
  14. Iron foods
    • liver
    • meat
    • eggs
    • potatoes
    • leafy green veggies
    • dried fruit
    • legumes
    • citrus fruit
    • whole grain
    • enriched breads & cereals
  15. Petechiae
    • pinpoint, nonraised, perfectly round area >2mm, purple, dark red or brown in color.
    • May indicate decrease platelets or clotting factors resulting in hemorrage into the skin.
  16. Pancytopenia
    decreased numer of RBC's, WBC's and platelets. Pt will need management of anemia, infections, and hemorrage
  17. shift to the left
    the existence of many immature cells when infections are severe, this means bone marrow is releasing more granulocytes as a compensatory mechanism to meet the increased demand.
  18. Neutropenia
    is a condition associated with a neutrophil count less than 1000 cells, severe neutropeni is associated with an (ANC) of less tha 500 cells. (absolule neutrophil count) This is associated with high risk of infection, bone marrow depression or disease process such as Leukemia
  19. Thrombocytopenia
    • Normal platelet count is 150,000-400,000
    • when count is <100,000, bleeding may occur. Spontaneous hemorrage is possible if<20,000
  20. Erythrocyte Sedimentation Rate (ESR or "sed rate")
    >ESR is common during acute & chronic inflammation reactions when cell destruction is increased.
  21. Hb 12-16(W)

    WBC differential
    Neutrophils 50%-70% (0.50-0.70)
    Eosinophils 2%-4% (0.02-0.04)
    Basophils 0%-2% (0-0.02)
    Lymphocytes 20%-40% (0.20-0.40)
    Monocytes 4%-8% (0.04-0.08)
  22. Platelet count 150,000-400,000