Lower GI

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Author:
dagillam
ID:
11780
Filename:
Lower GI
Updated:
2010-03-23 22:28:20
Tags:
Intestinal gas Diarrhea & Constipation
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Description:
DSM exam 3
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  1. Intestinal Gas therapy
    • Simethacone
    • a-Galactosaide
    • Activated Charcoal
  2. MOA of Simethacone
    reduce surface tension of gas bubbles
  3. MOA of a-Galactose
    natural food enzyme hat breaks down complex carbs in gas producing foods
  4. MOA if activated charcoal
    absorbs intestinal gas
  5. activated charcoal side effects
    • vomiting
    • hypersensitivity rxn
    • black stool
  6. simethacone dose
    40-360mg po pc & hs prn
  7. a-galactosidase dose
    150mg po wf
  8. activated charcoal dose
    • 500-520mg po pc ( may repeat in 2 hours)
    • 10g/day max
  9. Hemorrhoids treatment
    • Local anesthetics
    • vasoconstrictors
    • astringents
    • corticosteroids
    • protectants
    • analgesic/anesthetic ( camphor)
  10. Local anesthetics side effects
    • contact dermatitis
    • burning
    • stinging
    • hypersensitivity rxn
  11. vasoconstrictor SE
    HTN
  12. Corticosteroids SE
    • itching
    • stinging
    • hypersensitivity rxn
  13. analgesic/anesthetic SE
    contact exzema
  14. Protectants SE
    • skin sensitivity
    • irritation
  15. Protectants
    • Al Hydroxide
    • cocoa butter
    • glycerin
    • mineral oil
    • white petrolatum
    • shark liver oil
    • zinc oxide
    • topical starch
  16. astringents
    • witch hazel
    • zinc oxide
  17. Local Anesthetics
    • benzocaine
    • pamoxine
    • dibucaine
  18. Therapy for Constipation
    • Bulk laxatives
    • osmotic laxative
    • lubricant laxative
    • emollient/ stool softner
    • stimulant laxatives
    • saline laxatives
    • misc. products
  19. Bulk laxatives
    • psyllium
    • methylcellulose
    • polycarbophil
    • ( All first Line therapy)
  20. Bulk Laxative SE
    • abdominal cramps
    • constipation
    • flatulence
    • esophageal
    • bowel obstruction
  21. Bulk Laxatives MOA
    absorbs intestinal water, and forms a gel that promotes peristalsis and fecal elimination
  22. Psyllium dose
    2.5-3-gm/ day po in divided doses
  23. methylcellulose
    1-2gm po tid
  24. Polycarbophil dose
    1250mg po 1-4x/d
  25. Osmotic Laxatives
    • Glycerin(occasional us)
    • Lactulose (Chronic use)
    • polyethylene glycol 3350 (occasional us)
    • polyethylene glycol-electolyte soln (bowel cleansing)
    • sorbitol(occasional us)
  26. Osmotic laxative SE
    • flatulence
    • abdominal cramping
    • bloating
    • dehydration
    • electrolyte imbalance
  27. Lubricant Laxatives
    Mineral Oil (occasional constipation)
  28. Lubricant laxatives SE
    • abdominal cramps
    • NVD
    • decreased absorption of lipid soluble vitamins
    • lipid pneumonia w/ aspiration
  29. Emollient/stool softner drug
    Docusate (Colase)- Preventative therapy
  30. Emollient/ Stool Softener SE
    electrolyte imbalance
  31. Stimulant Laxatives
    • Senna (exlax)
    • Bisacodyl ( Dulcolax)
  32. Stimulant LAxatives SE
    • Abdominal cramping
    • fluid & electrolyte imbalances
  33. Saline laxative
    • Sodium Phosphate ( Fleet Enema, Fleet Phosphosoda)
    • MAgnesium CItrate ( Citroma)
    • Magnesium Hydroxide ( Mik of Magnesia, Phillips)
  34. MISC. Products
    • Castor Oil
    • Lubiprostone ( Amtiza)
  35. Castor Oil SE
    • Abdominal cramping
    • fluid & electrolyte imbalances
  36. Lubiprosterone ( Amtiza) SE
    • N/D
    • HA
    • abdominal pain
  37. Drugs used for Diarrhea
    • Adsorbants
    • -Polycarbophil
    • Antimotility ( Acute and Chronic associated with IBD)
    • -Loperamide
    • Opiates ( Acute and Chronic)
    • -Diphenoxylate/Atropine (Lomotil)
    • -Difenoxin/Atropine (Motofen)
    • -Paregoric
    • -Opium Tincture
  38. Antimotility Drugs SE
    • dizziness
    • constipation
  39. Opiate SE
    • drowsiness
    • dizziness
    • hypotension
    • constipation
    • respiratory depression
    • physical dependence

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