Chapter 145

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Author:
Anonymous
ID:
11790
Filename:
Chapter 145
Updated:
2010-03-23 22:05:13
Tags:
Toxicology
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Description:
General Approach to the Poisoned Patient
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  1. What is the mnemonic for Cholinergic OD?
    What are the common offending substances?
    • SLUDGE
    • Salivation
    • Lacrimation
    • Urination
    • Defecation
    • Gastrointestinal Cramping
    • Emesis/Bronchorrhea

    Organophosphates (pesticides) and Carbamate
  2. How do we treat Organophosphate OD?


    Atropine (increasing amounts dependent on symptoms) and Pralidoxime (2g)
  3. Describe the clinical picture of Serotonin Syndrome?
    Difficult to distinguish from cocaine use.

    AMS, Fever, tremor, hyperreflexia, ataxia, incoordination, diaphoresis, shivering
  4. What should you check for in the urine to confirm an ethylene glycol poisoning?
    Oxalate Crystals, along with the metabolic acidosis the patient would have.
  5. What are the medications that would truly benefit from activated charcoal?
    Which medications are of little benefit?
    • Benefit: Bblockers, CCB, TCA
    • No absorbtion from charcoal includes:
    • acids and alkalies, lithium, borates, hydrocarbons, metals (iron)
    • and ETHANOL

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