Viro Final III
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Where does influenzavirus replicate in the cell(2)?
What are the two subtypes of Type A influenzavirus(2)?
Hemagglutinin (HA) (16 different ones)
Neuraminidase (NA) (9 different ones)
Which influenza viruses are H7N7 and H3N8?
Eq Influenza 1
Eq Influenza 2
Where does equine influenza initially replicate?
epithelial cells of upper and lower respiratory tract
What are the clinical signs of an equine influenza infection (5)?
Serous nasal discharge
How is equine influenza virus infection diagnosed (8)?
Immunofluor & Immunohistochem
How is equine influenza infection prevented?
How is swine influenza infection prevented?
What are the two mechanisms of antigenic change in influenza virus (2)?
Genetic drift (point mutation)
Genetic shift (reassortment)
H1N1 is a triple reassortment of which flu viruses (3)?
Classical swine flu
Which animals are considered the host for canine distemper virus (hard pad disease) (5)?
How is canine distemper virus transmitted (3)?
Urine and feces
Where does initial virus replication occur in canine distemper virus?
Lymphoid tissue of respiratory tract
What are the clinical signs of canine distemper virus infection (7)?
How is canine distemper virus infection prevented (3)?
Modified live vaccine
MLV measles vaccine
Canarypox virus vectored vaccine
How is canine distemper virus infection diagnosed (3)?
Buffy coat analysis
Urine and bone marrow used for immunofluorescence
How is Hendra virus transmitted?
Direct contact with saliva or nasal secretions
What are the clinical signs of hendra virus infection (7)?
Frothy nasal discharge
Which animals are infected by hendra virus(2)?
Which animals are considered natural reservoirs for hendra and nipah virus?
Which viruses are in the genus Henipavirus(2)?
How is hendra virus infection diagnosed(#)?
Virus isolation in Vero cells
Virus neutralization test with two separate serum samples
How is hendra virus infection prevented?
Which animals are considered the host for Nipah virus?
What are the clinical signs of a nipah virus infection in pigs (3)?
How is Nipah virus diagnosed (5)?
Virus neutralization test
How is nipah virus infection prevented (3)?
Active surveillance and slaughter
Which animals are infected with Peste des Petits Ruminants virus(2)?
What are the clinical signs of PPR virus infection(5)?
Necrotic stomatitis and gingivitis
How is PPR virus infection diagnosed (3)?
Virus isolation in primary lamb kidney cells
How is PPR virus infection prevented(2)?
Vaccination using rinderpest virus tissue culture vaccine
Freeze-dried modified virus vaccine
Which animals are the host for Rinderpest (cattle plague)?
How is rinderpest virus transmitted(2)?
Contaminated water and air
Where does rinderpest virus initially replicate?
lymph nodes associated with nasopharynx
What are the clinical signs of rinderpest virus infection (5)?
(High mortality 100%)
How is rinderpest virus infection diagnosed (3)?
Detection of viral antigens
When was Rinderpest virus declared eradicated?
What is the host of newcastle disease (PMV-1)
What is the original newcastle disease virus classification (3)?
Mesogenic (moderately virulent)
Lentogenic (low virulence)
Which strains of Newcastle disease virus are reportable?
Velogens and Mesogens
Which strains of Newcastle disease virus are used as vaccines?
Lentogens (not reportable)
How is Newcastle disease controlled in the US?
Eradication (destroy infected poultry)
How is newcastle disease transmitted (3)?
What clinical signs do low virulence strains of Newcastle disease cause (3)?
What clinical signs do virulent strains of Newcastle disease cause (4)?
Watery green diarrhea
Head and Neck swelling
How is Newcastle disease infection diagnosed (5)?
Virus isolation in 9-11 day old chicken embryos
Fusion protein analysis
How is Newcastle disease infection prevented?
What is the primary cell of infection in equine arteritis virus and PRRS infection?
How is porcine reproductive and respiratory disease syndrome virus and equine viral arteritis transmitted (3)?
What is the most economically significant disease of swine in the US?
Porcine reproductive and respiratory syndrome (PRRS)
What are the clinical signs of PRRS (8)?
How is PRRS diagnosed (5)?
How is PRRS virus infection prevented (2)?
Killed vaccines reduce excretion of virus
Modified live vaccines
What are the clinical signs of equine viral arteritis (8)?
Fever, depression, anorexia
Edema of prepuce and scrotum
Lacrimation, conjunctivitis, photophobia
Stiff gait, ataxia
How is equine viral arteritis diagnosed (3)?
Virus isolation in RK-13 cells
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Viro Final III
Viro Final III
Viro Final III
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