What is meant by denaturation of a protein? How can proteins be denatured?
Any physical or chemical agent that destroys the stabilizing structures of a protein changes the conformation of the protein. This process is denaturation.
Denaturation The loss of the secondary, tertiary, and quaternary structures of a protein by a chemical or physical agent that leaves the primary structure intact.
Proteins can be denatured using heat, 6 M urea, detergents, acids and bases, salts, reducing agents, heavy metals, and alcohol. Anything that may affect the bonds that uphold the tertiary structure...