OTC Pharmacogenomics

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pszurnicki
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118557
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OTC Pharmacogenomics
Updated:
2011-11-29 14:23:16
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OTC Pharmacogenomics
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OTC Pharmacogenomics
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  1. Use of Saw Palmetto?
    • BPH
    • 5 Alpha reductase
  2. Use of St. Johns Wart?
    Depression
  3. Use of Ginkoba?
    • Alzehimers
    • Intermittent claudication
  4. Use of Echinacea?
    • Common Cold
    • enhances interleukins
  5. Use of Melatonin?
    • insomnia
    • jet lag
    • Serotonin like effects
  6. Use of Ephedra?
    • weight loss
    • decongestant
  7. Use of Ginseg?
    physical and mental enhancer
  8. Use of Garlic?
    • Heart disease--inhibit HMG coA reductase and ACE I
    • Cancer
  9. Use of Dihydroepiandrosterone?
    • androgen precursor
    • anti-aging
  10. Use of Kava?
    anti-anxiety--enhances GABA
  11. Use of FeverFew?
    Rx of migraine --> decrease LT's and PG's
  12. Milk Thistle?
    • Rx of liver disease
    • Rx of mushroom poisoning
  13. Drugs using the following receptors?
    5HT2
    5HT3
    5HT4
    5HT1A?
    5HT2A?
    5HT1D?
    • Cyprohepatadine-H1 blocker
    • Odansentron-anti-emetic
    • Tegaserod-IBD
    • Buspirone-GAD
    • Olanzapine-antipsychotic
    • Sumatriptan-migraine
  14. Antidotes for
    1Opiod
    2Benzo
    3Acetominophen
    4Fibrinolytic
    5Digoxin
    6Heparin
    7Warfarin
    8Methotrexate
    9Cyclophosphamide
    10INH
    • 1Nalexone
    • 2Flumenazil
    • 3N-acetylcysteine
    • 4aminocaproic acid
    • 5Digibind
    • 6Protamine sulfate
    • 7Vit K/Fresh Frozen Plasma
    • 8Leucovorin
    • 9Mesna
    • 10Pyridoxine-Vit B6
  15. 1Cholinergic(pesticide-Parathion)
    2Anticholinergic
    3Beta blocker
    4Cyanide
    5Methemoglobin
    6Methanol
    7Ethylene Glycol
    8Arsenic, Gold, Mercury
    9Lead
    10Copper
    11 Iron
    • 1Atropine +PAM
    • 2 Physostigmine
    • 3 Glucagon
    • 4Amyl Nitrate
    • 5Methylene Blue
    • 6Ethanol
    • 7 Fomepizol
    • 8Dimercarprol (BAL)
    • 9Succimer
    • 10Penicillamine/Trientene
    • 11 Deferoxamine
  16. Signs of Lead poisoning?
    • Lines on gingiva and epiphyseal plates
    • Encephalopathy
    • Anemia, Abdominal pains
    • Drop, wrist
  17. Rx for Lead Poisoning?
    • EDTA and Dimercaprol for adults
    • Succimer for kids
  18. Arsenic poisoning?
    • diarhea
    • vomiting
    • garlic breath
  19. Rx for Arsenic poisoning?
    Dimercaprol or Penicillamine
  20. Iron Poisoning?
    • necrotizing gastroenteritis
    • bloody diarhea
    • hematemesis
  21. Mee's lines are characteristic of poisoning with what materials?
    iron and other heavy metal poisoning
  22. Mercury Poisoning?
    • Pneumonitis
    • auditory and visual loss
    • ataxia
  23. Rx of Mercury Poisoning?
    • Dimercaprol
    • Succimer
  24. MOA of Morphine?
    inhibit release of Ach, NE, GLutamate, substance P
  25. Overdose with morphine?
    Rx for overdose
    • pinpoint pupil
    • respiratory depression
    • coma
    • Rx is nalexone
  26. 2 Alpha 2 agonists?
    • clonidine
    • alpha methyl dopa
  27. 2 HTN drugs give for pregnant women?
    • hydralazine
    • alpha methyl dopa
  28. Rx for overdose with cocaine and amphetamines?
    Effects of overdose?
    • haloperidol
    • hypervigilance, hallucinations
  29. Rx of withdrawal form cocaine and amphetamines?
    • bromocriptine
    • amantadine
  30. Rx of overdose with benzo or barbs?
    Flumazenil
  31. LSD acts on what receptors?
    serotonin
  32. Rx of LSD overdose?
    haloperidol or diazepam
  33. PCP acts on what receptors?
    Rx of overdose?
    • glutamate--increased depolarization
    • haloperidol
  34. Cannabis in marijuana and hash acts on what receptors?
    gaba
  35. Rx of Nicotine withdrawal?
    • nicotine patch
    • fluoxetine
    • bupropione
  36. Rx for caffeine withdrawal?
    • analgesics
    • lower caffeine intake
  37. Inhalants like glue, pain thinner, gasoline additives act on what receptor?
    Gaba
  38. What is the difference between Bupropion and Varenicline used for smoking cessation?
    • Bupropion--increase NE and Dopamine
    • Varenicline--partial agonist at nicotinic receptor
  39. What is the triad of ankylosing spondylitis?
    • sacroilliatis-can't stand
    • uveitis-can't see
    • aortic regurg- can't swim
  40. What infections besides chlamydia can cause Reiter's Syndrome?
    • Shigella
    • Salmonella
    • Campylobacter
  41. Pseudogout or Gout has needle shaped crystals?
    Rhomboid?
    • gout--needle--negative bifringent
    • pseudogout--rhomboid-positively bifringent
  42. In terms of deposition, where does Gout present in? Pseudogout?
    • gout--large toe
    • Pseudo--knee calium pyrophosphate
  43. Chondrocaliconosis or calcification of fibrocartilage is seen with what condition?
    Pseudogout--calcium pyrophosphate
  44. Causes of septic arthritis?
    • Gonoccocci
    • Aureus
    • Streptococcus
    • Heamophilus
  45. How does gonococcal arthritis present/?
    • Synovitis-knee
    • Tenosynovitis-hand
    • Dermatitis

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