Phys Exam III Sensation Control

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  1. What fibers detect temperature?
    • Adelta
    • C fibers
  2. Where in the skin temperature detected?
    In the dermis and the epidermis
  3. The _______________ integrates temperature information and relays it to the hypothalmus
    Reticular formation
  4. What is TPR?
    • Transient receptor potential
    • A large diverse family cation channels, detecting vision, taste. olfaction, hearing, touch and osmosensation
  5. __________ are involved in sensing temperature
  6. What allows for our ability to measure small temperature differences over a large temperature range?
    Different thermoTRP
  7. Both ___________ and ___________ may be involved in sensing temperature
    free nerve ending and specialized receptors cells
  8. ___________ have thermoTRP channels and can secrete bioactive substances, so may behave as specialized temperature receptors cells
  9. What acts as a proportional controller of body temperature?
  10. What integrates skin and core temperature and alters temperature via effectors for heat loss and heat gain?
  11. What are the effectors of heat loss?
    • Behavior
    • sweating
    • vasoconstriction
    • Vasodilation
  12. What are the effectors of heat gain?
    • Behavior
    • Shivering
    • Non-shivering thermogenesis
  13. What two systems control skin temperature??
    • The active vasodilator
    • The adrenergic vasoconstrictor
  14. What is the active vasodilator system?
    MOst of your skin (limbs, trunk) sympathetic signals cause blood vessels to dilate
  15. What is the adrenergic vasoconstrictor system?
    NOrepinephrine is toncially released with more release causing peripheral vasocontriction and less release causing vasodilation
  16. What does cold skin do to NE?
    Increases [] leading to vasoconstriction, conserving heat
  17. What does hot skin do to NE?
    Decreases [] leading to vasodilation to release heat
  18. What is the primary mechanism for control of body temperature?
  19. WHat are the main source of sweat for evaporative cooling and are particulary dense in acral regions?
    The eccrine sweat glands
  20. WHen does shivering occur? (specific)
    When cold temperature release the inhibition of the dorsomedial posterior hypothalmus by the POAH
  21. What causes a change in temperature in a fever?
    Change in the set point
  22. What causes a change in temperature for exercise?
    core temperature
  23. What does prolong periods of vasodilation lead to?
    Can lead to ischemic injury to the gut
  24. What do people do if they are acclimated to cold?
    • Lower core temperature threshold for shivering
    • have a lower shell conductance: reduced blood flow to the periphery
  25. What do people do if they are acclimated to heat?
    • Maintain a lower body temperature by sweating more
    • Associated with increased exercise
  26. What is the lewis hunting response?
    Is a rhythmic pattern of vasodilation and vasocontriction that allows fisherman to use their hands without excessive reduction of core body temperature
  27. What factors alter thermoregulation?
    • Exercise
    • age
    • drugs
    • lesions
  28. What is hypohydrotic ectoderm dyspasia?
    It is an X-linked recessive condition in individual have fewer and/or non-function sweat glands
  29. What is hyperthermia?
    An increase of core temperature due to failure of thermoregulation
  30. What is hypothermia?
    A decrease of core temperature due to failure of thermoregulation
  31. What is heat exhaustion?
    It is cardiovascular failure with no change in core temperature
  32. What is heat stroke?
    Hypothalmic failure caused by elevated core temperature
  33. How can people who are acclimated to heat maintain lower body temperature?
    By sweating more, can regulate their sweat production dependent on their level of dehydration and release less sodium in their sweat
  34. What in sweat is a critical determinant of the source of water in sweat and therefore of cardiovascular effects of sweating?
  35. [Na+] in sweat is a critical determinant of?
    The source of water in sweat and therefore of cardiovascular effects of sweating
  36. What are the classes of hypothermia?
    • Mild=(>32 oC)
    • Moderate=(>28 oC)
    • Severe=(<28 oC)
  37. How does alcohol affect hypothermia?
    • Hypothermia is linked to hypothermia is most often linked to alcohol
    • which depresses shivering
    • Increases peripheral vasodilation
    • Acts as a sedative
    • Resulting in reduced Tset
    • THermoregulatory precision
  38. How are the Sami in the Artic and Aborigines of Austrailia aclimized to the cold?
    • Habituation
    • Attenuation of metabolic response to cold, reduced shivering and Tcore
  39. How do korean divers aclimized to cold?
    They can tolerate lower core temperatures and have a lower thresholds for peripheral vasodilation
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Phys Exam III Sensation Control
Phys Exam III Sensation Control
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