Phys Exam III Sensation Control
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What fibers detect temperature?
Where in the skin temperature detected?
In the dermis and the epidermis
The _______________ integrates temperature information and relays it to the hypothalmus
What is TPR?
- Transient receptor potential
- A large diverse family cation channels, detecting vision, taste. olfaction, hearing, touch and osmosensation
__________ are involved in sensing temperature
What allows for our ability to measure small temperature differences over a large temperature range?
Both ___________ and ___________ may be involved in sensing temperature
free nerve ending and specialized receptors cells
___________ have thermoTRP channels and can secrete bioactive substances, so may behave as specialized temperature receptors cells
What acts as a proportional controller of body temperature?
What integrates skin and core temperature and alters temperature via effectors for heat loss and heat gain?
What are the effectors of heat loss?
What are the effectors of heat gain?
- Non-shivering thermogenesis
What two systems control skin temperature??
- The active vasodilator
- The adrenergic vasoconstrictor
What is the active vasodilator system?
MOst of your skin (limbs, trunk) sympathetic signals cause blood vessels to dilate
What is the adrenergic vasoconstrictor system?
NOrepinephrine is toncially released with more release causing peripheral vasocontriction and less release causing vasodilation
What does cold skin do to NE?
Increases  leading to vasoconstriction, conserving heat
What does hot skin do to NE?
Decreases  leading to vasodilation to release heat
What is the primary mechanism for control of body temperature?
WHat are the main source of sweat for evaporative cooling and are particulary dense in acral regions?
The eccrine sweat glands
WHen does shivering occur? (specific)
When cold temperature release the inhibition of the dorsomedial posterior hypothalmus by the POAH
What causes a change in temperature in a fever?
Change in the set point
What causes a change in temperature for exercise?
What does prolong periods of vasodilation lead to?
Can lead to ischemic injury to the gut
What do people do if they are acclimated to cold?
- Lower core temperature threshold for shivering
- have a lower shell conductance: reduced blood flow to the periphery
What do people do if they are acclimated to heat?
- Maintain a lower body temperature by sweating more
- Associated with increased exercise
What is the lewis hunting response?
Is a rhythmic pattern of vasodilation and vasocontriction that allows fisherman to use their hands without excessive reduction of core body temperature
What factors alter thermoregulation?
What is hypohydrotic ectoderm dyspasia?
It is an X-linked recessive condition in individual have fewer and/or non-function sweat glands
What is hyperthermia?
An increase of core temperature due to failure of thermoregulation
What is hypothermia?
A decrease of core temperature due to failure of thermoregulation
What is heat exhaustion?
It is cardiovascular failure with no change in core temperature
What is heat stroke?
Hypothalmic failure caused by elevated core temperature
How can people who are acclimated to heat maintain lower body temperature?
By sweating more, can regulate their sweat production dependent on their level of dehydration and release less sodium in their sweat
What in sweat is a critical determinant of the source of water in sweat and therefore of cardiovascular effects of sweating?
[Na+] in sweat is a critical determinant of?
The source of water in sweat and therefore of cardiovascular effects of sweating
What are the classes of hypothermia?
- Mild=(>32 oC)
- Moderate=(>28 oC)
- Severe=(<28 oC)
How does alcohol affect hypothermia?
- Hypothermia is linked to hypothermia is most often linked to alcohol
- which depresses shivering
- Increases peripheral vasodilation
- Acts as a sedative
- Resulting in reduced Tset
- THermoregulatory precision
How are the Sami in the Artic and Aborigines of Austrailia aclimized to the cold?
- Attenuation of metabolic response to cold, reduced shivering and Tcore
How do korean divers aclimized to cold?
They can tolerate lower core temperatures and have a lower thresholds for peripheral vasodilation
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