# Lab Final

The flashcards below were created by user ba on FreezingBlue Flashcards.

1. How do you find the sensitivity requirement?
• Put 6mg on one side of the balance and measure the deviation, then put 10g on both sides and add 6mg on one side and measure the deviation and compart to the deviation
• PLot the weight against the number of scale divisions shifted by each weight on graph paper
• Make a straight line and measure the weight that will cause a shift of one scale division
2. What is the equation for percent error?
Percent error = [(sensitivity requirement)(100)]/[quatity desired]
3. What is the equation for the smallest quantity to be weight?
Smallest quantity to be weight = [(Sensitivity requirment)(100)]/[Permissible percent of error]
4. What is the aliquot method?
• Weigh a multiple of the quantitydesired
• Dilute the multiple in a suitable manner
• Weigh or measure an aliquot of the final mixture
5. What is geometric dilution?
When mixing a small amount of drug (mg level) with a large amount of a second. the drug is placed in the mortar with equal bulk of the other ingrediant. The two ingredients are triturated until intimately mixed . Then equal bulk of the second ingredients is added to the mixture and the powders are intimately mixed
6. Define: capsule
Are solid dosage forms in which the drug substances is enclosed in either a hard or solf , soluble container of shell of a suitable form of gelatin
7. What is the punch method?
• Manually filling capsules one by one
• Flatten the powder so that it is no greater than 1/3 the length of the capsule
8. What is the most common solid dosage form?
Tablet
9. Define: tablet
Unit form of solid drugs prepared by compaction
10. Define: stick
• topical medicated dosage form for adminsitrating topical medications
• Chapstick
11. What are the two methods for preparing onintments?
• Fusion
• Incorporation
12. WHat is the incorporation method?
The components of the ointments are mixed together by various means until a uniform preparation has been atained
13. Define: ointment
Are semi-solid preparations containing dissolved or dispersed drugs or no drugs intended for external application to the body
14. Define: cream
• are emulsified ointments
• Viscous liquid or semisolid emulsions systems either oil in water or the water in oil "creamy white" appearance
15. What method is generally used to make creams?
• Fusion
• (THe oil and aqueous phases are heated separately, the emulsifier agent is added to the aqueous phase and the emulsion is formed by slow addition of the oil phase)
16. Define: lotion
are usually liquid suspensions of emulsions intended for external application to the skin and mucosa
17. Define: pastes
basucally ointments into which a higher percent of insoluble solids have been added, as much as 50% by weight in some instances
18. cream: cetyl ester wax
stiffening agent
19. cold cream: mineral oil
oleagenous vehicle
20. cold cream: water
aqueous vehicle
21. cream: sodium borate
emulsifing agent
22. paste: starch
stiffening agent
23. lotion: zinc oxide, calamine
active ingredients with protectant and astringent properties
24. lotion: glycerin
levigating agent
25. lotion: microcrytalline cellulose
suspending agent
26. lotion: carboxymethylcellulose
suspending agent
27. lotion; calcium hydroxide solution
• aka lime water
• vehicle with antringent property
28. Define: gel
• are semisolid systems consisting of suspnsions made up of either small inorganic particles or large organic molecules interpenetrated by a liquid
• are semigrid systems in which the movement of the dispensing medium is restricted by an interlacing three dimensional network
29. What gelling agent is primarly used in aqueous systems
carbomer
30. gel: hydroxypropylcellulose
gelling agent
31. gel: propylene glycol
levigating agent
32. gel: polysorbate 80
• tween 80
• solubilizing agent
33. gel: 70% isopropyl alcohol
solvent, vehicle
34. gel: carbomer 934
gelling agent
35. gel: alcohol
solvent
36. gel: p water
solvent
37. define: suppositories
are solid dosage forms intended for insertion into body orifices where they melt, soften, or dissolve and exert localized or systemic effects
38. What are the three classes of suppository bases?
• fatty/oleagenous
• water miscible bases
• miscellaneous, combination of lipophilic and hydrophilic bases
39. What are fatty/oleagenous bases?
• cocoa butter
• hydrogenated fatty acids of vetgetable oils
• kernal oil
• fatty acid glyceride such are glyceryl monopalmitate
40. What suppository base melts body temperature to release the medicament
fatty/oleagenous bases
41. what is an example of water-miscible base?
polyethylene glycol
42. What type of suppository base dissolve in the body cavity?
water miscible
43. What are the two methods of making suppositories?
• molding from a melt
• cold compression
44. suppository: PEG
water miscible bases
45. define: solutions
as liquid preparations that contain one or more soluble chemical substances usually dissolved in water or water miscible pharmaceutical solvents and that do not, by reasons of their ingredients, method of preparation or used, fall into other groups of product
46. define: elixirs
aqueous pharmaceuticl solutions sweetened hydroalcoholic
47. define: syrups
aqueous pharmaceutical solutions containing sugar
48. What is a simple solution?
composed of one substances
49. what is compound solution?
solution containing more than on esolute
50. What is a chemical solution?
solutions whose components are the product of a chemical reaction
51. What is a saturated solution?
Solutions containing all the solute that the solvent will hold
52. define: solvent
compose the major portion of a solution
53. Drugs adminstered as __________ liquids are generally absorbed much more rapidly
aqueous liquids
54. solution: polysorbate 20
levigating agent
55. solution: ethanol 95%
co-solvent
56. solution: sodium saccharin
sweetner
57. solution: sodium benzoate
antimicrobial
58. solution: sorbitol 70% solution
sweetner
59. solution: tween 80
solubilizing agent
60. solution: sodium saccharine
sweetener
61. solution: lemon oil
flavor agent
62. solution: citric acid
acidifier/stabilizer
63. solution: glycerin
thickening
64. solution: methylparaben
preservative
65. What are the components of an syrup?
• sugar
• antimicrobial preservative
• flavorants
• colorants
66. What is the concentration of sugar in simple syrupe NF
85%
67. define: elixir
are clear sweetened hydroalcoholic solutions intended and are usually flavored to enhance pala
68. What percent of alcohol is needed to make it self preserved?
10 to 12 percent
69. elixir: cocoa
flavor
70. elixir: sucrose
sweetner
71. elixir: glycerin
levigating agent
72. elixir: sodium chloride
stabilizer
73. elixir: vanillin
flavor
74. elixir: sodium benzoate
antimicrobial
75. syrup: benzoic acid
antimicrobial preservative
76. syrup: disodium calcium EDTA
chelating agent, stabilizer
77. syrup: propylene glycol
thickening agent, co-solvent, sweetner
78. syrup: alcohol
• co-solvent
• antimicrobial
79. syrup: saccharin
sweetner
80. define: suspension
are preparations containing finely divided drug particles (suspensoid) distributed somewhat uniformly throughout a vehicle (dispersion medium)
81. what are the problems presented to a suspension?
• aggregation
• sedimentation
• impaction
82. suspension: glycerylmonostearate
suspending agent
83. suspension: glycerin
levigating
84. suspension: sodium lauryl sulfate
surfactant
85. suspension: methylparaben
preservative
86. suspension: propylparaben
preservative
87. define: emulsions
is a dispersion in which the dispersed phase (internal phase) is composed of smal globules of a liquid distributed throughout a vehicle/medium (external phase) in which it is imiscible
88. emulsion: cottonseed oil
oleagenous phase solvent
89. emulsion: polyoxyethylene sorbitan-monostearate (tween 60)
emulsifier agent
90. emulsion: sorbitan monooleate
emulsifier agent
91. emulsion: sodium saccharin
sweetener
92. emulsion: methylparaben
preservative
93. emulsion: sodium benzoate
preservative
 Author: ba ID: 119083 Card Set: Lab Final Updated: 2011-11-28 03:47:54 Tags: Lab final Folders: Description: Lab final Show Answers: