DM Drugs

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Author:
pszurnicki
ID:
119394
Filename:
DM Drugs
Updated:
2011-11-28 15:12:11
Tags:
DM drugs
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Description:
DM Drugs
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  1. 3 1st generation sulfonylureas?
    • Tolbutemide
    • Acetohexamide
    • chlorpropamide
  2. 3 drugs causing SIADH?
    • carbamezapine
    • chlorpropamide
    • cyclophosphomide
  3. 3 2nd generation sulfonylureas?
    • glipizide
    • glyburide
    • glimepiride
  4. MOA of Metformin?
    S/e?
    • increase tissue insulin sensitivity
    • decrease gluconeogenesis
  5. MOA of Posiglitazone, Rosiglitazone?
    • increase insulin sensitivity
    • decrease gluconeogenesis
  6. MOA of nateglimide?
    Repaglimide?
    increase insulin release
  7. MOA of increasing tissue sensitivity to insulin by Posiglitazone, Rosiglitazone?
    by binding to PPAR(perixosome proliferating activating receptor) which increase transcription of genes
  8. MOA of Pramlitanide?
    inhibits glucagon relase
  9. MOA of Exanatide?
    • increase insulin release
    • decrease glucagon release
  10. What is given before a meal?
    • Nateglinide
    • Rateglinide
  11. NPH is given with what before the mea?
    regular insulin
  12. Rapid acting insuin?
    • Aspart
    • Lispro
  13. Intermediate acting insulin?
    • NPH
    • lente +zinc
  14. Slow acting insulin?
    • ultralente
    • insulin glargine (lantus)
    • Detemir

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