Three bypass reactions OF Gluconeogenesis.
1. Synthesis of phosphoenolpyruvate (PEP) via the enzymes pyruvate carboxylase and PEP carboxykinase. NEAR BOTTOM
2. Conversion of fructose-1,6-bisphosphate to fructose-6-phosphate via the enzyme fructose-1,6-bisphosphatase. 3RD FROM TOP.
3. Formation of glucose from glucose-6-phosphate via the liver and kidney-specific enzyme glucose-6-phosphatase. NEXT TO SECOND STEP.