hepatic.txt

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Author:
nsmallwood
ID:
119732
Filename:
hepatic.txt
Updated:
2011-11-29 23:02:38
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absite
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Description:
liver questions
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  1. most common hepatic artery variant
    replaced right off of sma
  2. middle hepatic vein drains
    V and IVa and sometimes VIII
  3. only water soluble vitamin stored in liver
    B12
  4. enzyme turning cholesterol to bile acids
    7-alpha hydroxylase
  5. primary bile acids
    cholic and chenodeoxycholic
  6. secondary bile acids
    deoxycholic, lithocholic
  7. main biliary phospholipid
    lecithin
  8. defect in anionic transporter cMOAT
    dubin-johnson
  9. deficiency in storing conjugated bilirubin
    Rotor syndrome
  10. definition of acute liver failure
    hepatic disease plus coagulopathy and encephalopathy
  11. encephalopathy caused by
    inability to metabolize ammonia, mercaptanes, false NTs
  12. outcome of liver failure determined by
    encephalopathy
  13. criteria for liver txp in acetaminophen poisoning
    pH<7.3 or PT>50 +Cr>3.4 +stage III or IV coma
  14. criteria for liver txp in other causes of acute hepatic failure
    • any 3
    • age <10 or >40
    • halothane, drug or idiopathic
    • jaundice>7 days
    • PT>25
    • bilirubin>17.5
  15. pathophys of portal htn
    stellate cell causing capillarization of space of disse also the release of endothelin 1
  16. MELD score uses what factors
    bilirubin, inr, cr
  17. most prognostic test of liver function
    aminopyrine breath test
  18. what MELD score do patients begin to derive benifit from a transplant
    >15
  19. nutmeg liver with fibrosis sparing the portal vein
    cardiac cirrhosis

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