Inhaled corticosteroids

Card Set Information

Author:
mpgcuenca
ID:
119770
Filename:
Inhaled corticosteroids
Updated:
2011-11-30 02:57:54
Tags:
Asthma COPD
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Description:
Inhaled corticosteroids
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  1. Inhaled corticosteroids
    • Budesonide, dry powder
    • Triamcinolone
    • Fluticasone, dry powder and pressurized aerosol
    • Mometasone, dry powder
    • Flunisolide
    • Beclomethasone
    • Ciclesonide
  2. MoA
    • Anti-inflammatory
    • Suppress local inflammatory response
  3. Indications
    • Controller medication for asthma
    • Considered the first line treatment for asthma with the exception of intermittent or exercise induced bronchospasm (EIB)asthma.
    • Most effective anti-inflammatory medication, along with systemic corticosteroids, for asthma.
  4. SEs
    • Risk of SEs increase with increasing dose
    • Oral candidiasis
    • Dysphonia (difficulty using voice)
    • Reduced bone density (especially in women)
    • Minor reduction in lipid and carbohydrate metabolism
    • Skin thinning
    • Purpura
    • Potentially hypothalamic-pituitary adrenal axis suppression but generally clinically insignificant
  5. Contra
    • Acute exacerbation or status asthmaticus
    • Rinse mouth & spit after use to decrease candidiasis infx

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