Anti-IgE therapy

Card Set Information

Author:
mpgcuenca
ID:
119774
Filename:
Anti-IgE therapy
Updated:
2011-11-30 03:21:33
Tags:
Asthma COPD
Folders:

Description:
Anti-IgE therapy
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user mpgcuenca on FreezingBlue Flashcards. What would you like to do?


  1. Anti-IgE drug
    Omalizumab
  2. MoA
    • IgG monoclonal antibody which inhibits IgE binding to the high-affinity IgE receptor on mast cells and basophils.
    • The activation and release of mediators in the allergic response are decreased.
  3. Indication
    Asthma refractory to standard therapy
  4. SEs
    • “Box warning” for anaphylaxis occurring 2-24hrs after administration
    • Only given in healthcare setting by trained personnel with supplies available to treat anaphylaxis
    • Patients also are required to have injectable epinephrine available at home and instructed on its use
    • Monitor patients who are at risk for helminth infections may exacerbate
  5. Contra
    • Anaphylaxis
    • Acute bronchospasm
    • Status asthmaticus
  6. Drug interactions
    • None documented at current time
    • Note – has not been documented to be cost effective treatment. Optimal use and indication still not clearly

What would you like to do?

Home > Flashcards > Print Preview