Card Set Information
IgG monoclonal antibody which inhibits IgE binding to the high-affinity IgE receptor on mast cells and basophils.
The activation and release of mediators in the allergic response are decreased.
Asthma refractory to standard therapy
“Box warning” for anaphylaxis occurring 2-24hrs after administration
Only given in healthcare setting by trained personnel with supplies available to treat anaphylaxis
Patients also are required to have injectable epinephrine available at home and instructed on its use
Monitor patients who are at risk for helminth infections may exacerbate
None documented at current time
Note – has not been documented to be cost effective treatment. Optimal use and indication still not clearly