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How does an atrial myxoma present?
- syncopal attacks
- embolization of a thrombus
- acute phase protein symptoms i.e anemia, malaise, high ESR, amyloidosis
What are the types of amyloidosis?
- Transthyretin in the elderly
- Amylin in DM
- light chain Ig in MM
- SSA in chronic inflammation
- dialysis associated beta 2 macroglobulin
- calcitonin in medullary carcinoma
5 Tumors of the heart?
- Papillary Fibroelastoma
Why are cardiac abnormalities like fibrosis due to carcinoid syndrome only manifested on the right side of the heart?
bc the lung has monoamine oxidase which inactivates 5HT and bradykinin and they cannot cause the pathologies on the left side of the heart
What is the difference between micronodular and macronodular cirhosis?
- macronodular is produced by fast acting agents--hepatitis
- micronodular is produced by chronic, insidious causes i.e
3 Causes of endocarditis?
- bacterial-Staph aureus
- autoimmune-as in SLE--libman-sac endocarditis
- malignant thrombi
Presentation of Bacterial endocarditis?
- Roth spots
- Oslers nodes
- Janeway lesions
- Nail bed hemorrhages
What are the defects seen in Down syndrome?
- CNS-mental retardation, Alzheimers
- GI--Hirshsrpung, Duodenal Atresia
- Blood-ALL, AML
What is the mode of inheritance for Cleft palate, cleft Lip, pyloric stenosis?
Cause for Pyloric stenosis in the adult?
antral gastritis producing fibrosis and stricture