Direct-Acting Sympathomimetics

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Author:
jaguavai
ID:
120062
Filename:
Direct-Acting Sympathomimetics
Updated:
2011-12-01 11:06:28
Tags:
Pharm 420
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Description:
Direct-Acting Sympathomimetics
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  1. Alpha 1 agonist clinical applications (5)
    • Nasal and ophthalmic decongestion
    • Hemostasis (stop bleeding)
    • Restoring blood pressure
    • Adjuncts to local anesthetics
    • Mydriasis
  2. Alpha 1 agonist adverse effects (5)
    • Reflex bradycardia
    • Hypertension
    • Necrosis following extravasation
    • Exacerbate BPH and Glaucoma
  3. Alpha 2 agonist clinical applications (3)
    • Hypertension
    • Glaucoma
    • ADHD
  4. Alpha 2 agonist Major Adverse Effects (6)
    • Sedation
    • Dry mouth/eye
    • Hypotension
    • Sexual dysfunction
    • Depression
    • AV block
  5. Beta 1 agonist clinical applications (4)
    • Shock
    • Cardiac arrest
    • Heart failure
    • AV Block
  6. Beta 1 agonist major adverse effects (3)
    • Angina
    • Tachycardia
    • Arrhythmias
  7. Beta 2 agonist clinical applications (2)
    • Asthma and COPD
    • Delay premature labor
  8. Beta 2 agonist major adverse effects (3)
    • Hyperglycemia in diabetics - increased gluconeogenesis and glycolysis, PT can't make insulin to compensate
    • Tremors, usually transient
    • Cardiac arrhythmias due to hypokalemia
  9. Dopamine agonist clinical applications (2)
    • Cardiogenic shock
    • CHF

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