Derm Path I

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Derm Path I
2011-12-03 11:16:52
Derm Path

Derm Path I
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  1. Macule:
    Circumscribed lesion of <5 mm in diameter characterized by flatness and usually discolored (often red)‏
  2. Patch:
    Circumscribed lesion of >5 mm in diameter characterized by flatness and usually discolored (often red)
  3. Papule:
    Elevated dome-shaped or flat-topped lesion <5 mm across.
  4. Nodule:
    Elevated lesion with spherical contour >5 mm across.
  5. Plaque:
    Elevated flat-topped lesion, usually >5 mm across (may be caused by coalescent papules).
  6. Vesicle:
    Fluid-filled raised lesion <5 mm across.
  7. Bulla:
    Fluid-filled raised lesion >5 mm across.
  8. Blister:
    Common term used for vesicle or bulla.
  9. Pustule:
    Discrete, pus-filled, raised lesion.
  10. Wheal:
    Itchy, transient, elevated lesion with variable blanching and erythema formed as the result of dermal edema.
  11. Scale:
    Dry, horny, plate-like excrescence; usually the result of imperfect cornification (i.e., keratinization).
  12. Lichenification:
    Thickened and rough skin characterized by prominent skin markings; usually the result of repeated rubbing in susceptible persons.
  13. Excoriation:
    Traumatic lesion characterized by breakage of the epidermis, causing a raw linear area (i.e., a deep scratch)‏
  14. Onycholysis:
    Separation of nail plate from nail bed.
  15. Hyperkeratosis:
    Thickening of the stratum corneum, often associated with a qualitative abnormality of the keratin.
  16. Parakeratosis:
    Modes of keratinization characterized by the retention of the nuclei in the stratum corneum. On mucous membranes, parakeratosis is normal.
  17. Hypergranulosis:
    Hyperplasia of the stratum granulosum, often due to intense rubbing.
  18. Acanthosis:
    Diffuse epidermal hyperplasia.
  19. Papillomatosis:
    Surface elevation caused by hyperplasia and enlargement of contiguous dermal papillae.
  20. Dyskeratosis:
    DYSPLASIA, Abnormal keratinization occurring prematurely within individual cells or groups of cells below the stratum granulosum..
  21. Acantholysis:
    Loss of intercellular connections resulting in loss of cohesion between keratinocytes.
  22. Spongiosis:
    Intercellular edema of the epidermis.
  23. Hydropic swelling (ballooning):
    Intracellular edema of keratinocytes.
  24. Exocytosis:
    Infiltration of the epidermis by inflammatory or circulating blood cells.
  25. Erosion:
    Discontinuity of the skin exhibiting incomplete loss of the epidermis.
  26. Ulceration:
    Discontinuity of the skin exhibiting complete loss of the epidermis and often of portions of the dermis and even subcutaneous fat.
  27. Vacuolization:
    Formation of vacuoles within or adjacent to cells; often refers to basal cell-basement membrane zone area.
  28. Lentiginous:
    Referring to a linear pattern of melanocyte proliferation within the epidermal basal cell layer. Lentiginous melanocytic hyperplasia can occur as a reactive change or as part of a neoplasm of melanocytes.