CV Path

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Author:
jlolson83
ID:
120421
Filename:
CV Path
Updated:
2011-12-03 18:47:27
Tags:
CV
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Path
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  1. Giant Cell Vasculitis
    • Most common in older adults
    • Large to medium vessels (temporal, ophthalmic, aorta)
    • Nodular intimal thickening
    • Granulomatous infiltrate
    • Skip lesions
    • Fever, pain, vision changes, HA
    • Treat with steroids
  2. Takayasu Arteritis
    • Granulomatous
    • Aorta and main branches
    • Pts <50
    • Pulseless disease when transmural fibrosis
  3. Polyarteritis nodosa (PAN)
    • Small to medium muscular arteries
    • Immune complex mediated (30% hep B, no ANCA)
    • Young adults
    • Segmental transmural necrotizing (fibrinoid) inflammation. Neutrophilic infiltrate
  4. Kawasaki syndrome
    • Mucocutaneous lymph node syndrome
    • Erythema and edema in hands and feet. Enlarged lymph nodes.
    • All arteries, mostly medium. Often coronary.
    • Pts <4y
  5. Microscopic Polyangiitis
    • Leukocytoclastic vasculitis
    • Breakdown of neutrophils
    • Small vessels
    • Kidneys and lungs and more
    • pANCA often, no immune complex deposition
    • Fibrinoid necrosis of media
  6. Churg-Strauss Syndrome
    • Allergic granulomatosis and angiitis
    • Small vessels
    • Lungs
    • Increased eosinophils
    • Fibronoid necrosis, extravascular granulomas in lung
    • pANCA
  7. Wegener Granulomatosis
    • 1. Acute necrotizing granulomas of respiratory tract
    • 2. Necrotizing or granulomatus vascultiis of sm/med vessels
    • 3. Renal disease
    • cANCA
    • men>women
  8. Thromboangitis Obliterans
    • Buerger
    • sm/med vessels
    • Pt = Smokers <35y
    • Nodular phlebitis, cold sensitivity
  9. Glomus tumor
    • distal digits
    • modified sm m cells
    • benign, painful lesion
  10. Bacillary angiomatosis
    • immunocompromised peeps (AIDS)
    • Bartonella
  11. Kaposi sarcoma
    • 1. chronic, old easter europeans
    • 2. lymphadenopathic, african kids
    • 3. transplant immunosuppression
    • 4. AIDS associated
  12. pANCA
    • Microscopic polyangiitis (leukocytoclastic vasculitis)
    • Churg-Strauss syndrome

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