Pathophys Test 2

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Author:
cgordon05
ID:
12104
Filename:
Pathophys Test 2
Updated:
2010-03-26 22:41:32
Tags:
Intestines
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Description:
Intestines
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  1. If you patient had history of diverticular disease but at present there was not an acute inflammatory condition, what dietary recommendations would you make and why? (p.27)
    • High fiber diet - increase transit through GI tract
    • Wheat bran, fruits, vegetables, legumes
    • Women = 25g/day, Men = 38g/day
  2. Clinical manifestations of Appendicitis (p.31)
    • Epigastric, periumbilical, cramping pain
    • - may be diffuse
    • - initially RLQ
    • Nausea and vomiting
    • Low-grade fever
    • Pain shifting to RLQ with point tenderness
  3. Inflammatory Bowel Diseases (p.27)
    • Term used for Crohn's disease and ulcerative colitis.
    • Common features:
    • - inflammation of bowel
    • - no proven causal agent
    • - pattern of familial occurrence
    • - systemic manifestation
  4. How does Crohn’s contribute to malabsorption, malnutrition, and weight loss? (p.27-28)
    • Any portion of GI tract may be affected - most often small intestine and colon
    • Transmural - all 3 layers of bowel involved
    • Segments of inflamed tissue separated by normal tissue - cobblestone and patchy - interferes with absorption leading to malnutrition and weight loss
  5. What is distinction between Crohn's disease and ulcerative colitis based on anatomic localization and histologic appearance? (p.29)
  6. Identify symptoms and theories of Irritable Bowel Syndrome (IBS). (p.29)
    • Symptoms:
    • - chronic abdominal pain - crampy sensations with periodic exacerbations
    • - associated with episodes of diarrhea and constipation
    • Theories:
    • - visceral hypersensitivity
    • - abnormal GI motility (esp. colon)
    • - emotional stress
    • - cholecystectomy (perpetual drip of bile into duodenum)
  7. What are the risk factors, sign/symptoms of Celiac disease? (p.34)
    • Risk factors - genetic predisposition – HLA-DQ2 and HLA-DQ8 gene alleles
    • Signs and symptoms:
    • - Chronic diarrhea
    • - Abdominal distention
    • - Painful stomach bloating
    • - Foul-smelling stools
    • - Fatigue, extreme lethargy
    • - Weight loss
    • - Muscle wasting
    • - Vomiting
    • - Irritability
    • - Children – not grow normally, not absorbing nutrients
  8. What is the pathogenic process considered to initiate intestinal damage in Celiac disease?
  9. If you suspected celiac disease in your patient, what initial test would be most appropriate to perform?
    • Serologic screening for IgA transglutaminase antibody test (IgATTG)
    • Followed by endoscopic biopsy of duodenal mucosa
  10. Once confirmed, what is the treatment for celiac disease?
    • Lifetime gluten-free diet
    • CAN eat: fish, chicken, milk, veggies, corn, rice, eggs, fresh meats, unprocessed cheeses, dry beans, fruits

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