FSCN.ch.12.fat.soluble

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xiongav
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121136
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FSCN.ch.12.fat.soluble
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2011-12-05 23:21:12
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FSCN 12 fat soluble
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FSCN.ch.12.fat.soluble
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  1. Vitamin A.(Retinoids/Carotenoids)

    *Describe characteristics of Retinoids.
    -Functions
    • Retinoids:
    • -Fish products
    • -3 forms: retinal, retinol, retinoic acid

    • Functions:
    • -Growth & Dev.
    • -*VISION
    • -*DERMATOLOGY (psoriosis/acne)
    • -cell signaling
    • -immune function
  2. Vitamin A.(Retinoids/Carotenoids)

    Retinoids Deficiency
    • ***LEADING CAUSE
    • OF ACCIDENTAL BLINDNESS IN THE WORLD
    • -1/2 million children in the world in poor countries
    • -Night blindness
    • -Xerophthalmia: permanent blindness
    • -Follicular hyperkeratosis (skin disease): due to loss epithelial cells
  3. Vitamin A.(Retinoids/Carotenoids)

    Toxicities
    • -Hypervitaminosis A
    • ***Teratogenicity (causing birth defects)
    • -By use of topical skin treatments during pregnancy
  4. Vitamin A.(Retinoids/Carotenoids)

    Describe characteristics

    Toxicities

    Food Sources
    ***ANTI-OXIDANT

    ***NO TOXICITIES!

    • Food sources:
    • -VEGGIES
    • *Beta-carotene is the MOST COMMON
  5. Vitamin D (NOT ALWAYS RQ'D IN DIET)
    ***Vitamin D increases when calcium decreases
    ***Very big research focus right now – much disagreement

    Dietary Sources

    ***Travels toliver & kidney where it is further metabolized to form active form – CALCITRIOL

    Deficiency

    Toxicity
    • Dietary Sources
    • -Fatty fish

    • Deficiency:
    • -Children: RICKETS
    • -Adults: OSTEOMALACIA (softbones)

    • Toxicity:
    • -Not from dietary sources or sunlight
    • -OCCURS w/ supplementation
    • -Can cause over absorption of calcium and phosphorus
    • -Can be fatal
  6. Vitamin E.

    Functions

    Deficiency
    • Functions: ANTI-OXIDANT
    • -Helps prevent peroxidation of unsaturated fatty acids.
    • -Often called “REACTIVE OXYGEN SPECIES (ROS; free radicals)

    -Se & Vit. E prevents Reactive Oxidation.

    • Deficiency:
    • Anemia: deficient in red blood cells.
  7. Vitamin E.

    Diseases

    Toxicities

    Food sources
    • Diseases:
    • 1) Hemolytic - anemia – rare in humans
    • 2) Preterm infants’HIGHEST RISK groups due to limited storage at birth.

    • Toxicities:
    • (Blood clotting)
    • -Interfere w/ Vitamin K & causes hemorrhaging (insufficient blood clotting)

    Foods: Nuts, Plant sources
  8. Vitamin K.

    Menaquiones/Phylloquinones (MAIN)
    • Menaquinones:
    • -fish oils
    • -ONLY vitamin that can be synthesized by GUT BACTERIA

    • Phylloquinones (MAIN):
    • -Green leafy vegetables
    • -MOST biologically ACTIVE form.
  9. Vitamin K.

    Functions

    Deficiency

    Toxicity
    • *Functions:
    • ***BLOOD CLOTTING
    • -Bone health
    • -Anti-inflammatory

    • Deficiency:
    • RARE, long term anti-biotic use
    • ***Most children given Vitamin K injections.

    Toxicity: NONE
  10. Does LEPTIN relates to all reproductive organs and cycles?
    Yes.

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