-
Topical Carbonic Anhydrase Inhibitors
- Dorzolamide (TRUSOPT)
- Brinzolamide (AZOPT)
-
MoA
- Inhibit CA (isoenzyme II) in ciliary body epithelium. This reduces the
- formation of bicarbonate ions, fluid transport and IOP.
-
SEs
- Fewer than systemic agents, burning or stinging of the eye, conjunctivitis,
- eyelid edema. Fewer complaints with brinzolamide, shake bottle before
- use.
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