Card Set Information
Cholinergic agents (Mitotics)
Carbachol (MIOSTAT, ISOPTO CARBACHOL etc.)
Pilocarpine (AKARPINE, PILOCAR, PILOSTAT etc.)
Pilocarpine and carbachol are used to treat glaucoma. Carbachol and
acetylcholine are designated for intraocular use for miosis in surgery.
Mean reductions in IOP of 20 – 30%.
Contraction of the ciliary muscles are mediated by muscarinic
cholinomimetic agents. Contraction of the ciliary muscles puts tension on
the trabecular meshwork, opening its pores and facilitate outflow of the
aqueous humor into the canal of Schlemm. This increased outflow
reduces intraocular pressure and thus muscarinic cholinomimetics are
useful agents to treat glaucoma.
Ciliary muscle spasm with resultant brow ache and induced myopia,
headaches can occur from the iris and ciliary body contraction, pupillary
constriction, blurred vision, cataract formation, sweating, headache,
tremor, excess saliva production, diarrhea,abdominal cramps and nausea.