Chapter 6 Patho
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Antigenitcity depends on:
- chemical structure
When antigen binds to its appropriate antibody:
- agglutination may ocur
- phagocytosis may occur
- antigen neutralization may occur
Antibodies are produced by
An immunoglobulin contains:
two heavy and two light polypeptide chains
The antibody class having the highest concentration in the blood is
Which antibody is matched with its appropriate role?
IgM/ first to challenge the antigen
The primary immune response involves :
a latent period followed by peak antibody production
Which cells are phagocytic
When a child develops measles and aquires an immunity to subsequent infections, the immunity is:
What is adaptive immunity?
is a state of protection, primarily against infectious agents. that differs from inflammation by being slower to develop, being more specific and having memory that makes it much longer lived
What is natural immunity?
it is innate resistance and quired immunity is gained after birth
What are antigens?
they are molecules that react with components of the immune response such as antibodies and receptors on B and T cells. Most antigens can induce an immune response and thus antigens are also immunogens
What are self-antigens?
they are antigens on an individual's own cells. The individuals immune systems does not normally recognize self -antigens as immunogenic, conditions known as tolerance.
What is the Hummoral Immune Response?
- it is provided by molecules (antibodies) produced by the Bcells
- Antibodies are plasma glycoproteins that can be classified by chemical sturcture and biologic activity as IgG, IgM, IgA, IgD, IgE
What is Cell-Mediated Immune Response?
- T cells are responsible for the cell mediated immune response
- there are several types: cytotoxic T (Tc), regulatory, T helper (Th), and T suppression, and memory cells.
- Development of cell mediated or humoral immune responses usually depends on population of Th cells
How do T Cells respond?
T Cells have antigen specific receptors that must see antigen presented on cell surfaces by special antigen prestenting molecules of the major hisocompatibility complex (MHC molecules)
Where do T and B cells migrate to?
Immunocompetent T and B cells migrate from primary lymphoid organs into the circulation and secondary lymphoid organs to await antigen.
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