Baker's Exam 3: GI System Medications

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Author:
kmaher
ID:
122094
Filename:
Baker's Exam 3: GI System Medications
Updated:
2011-12-09 02:00:43
Tags:
Dental Therapeutics
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Description:
GI system medications
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  1. What mechanism category do the following belong: Cimetidine, Famotidine, Nizatidine, and Ranitidine?
    H-2 Antagonists (Reduces GI acid)
  2. What mechanism category do the following belong: Esomeprazole, Lansoprozole, Omeprazole, Pantoprazole and Rabeprozole?
    Proton Pump Inhibitors (PPIs): "Prazoles"
  3. What are the common dentally significant adverse effects for both H-2 antags. and PPIs?
    • HA and GI are the primary effects for both
    • *but drug INTX w/dental drugs fluconazole and Triazolam*
  4. What are the dental tx impacts for H-2 antagonists?
    • All dec. absorption of Ketoconazole, but not Fluconazole
    • Cimetidine: dec clearance of BZDPs, Lidocaine, Carbamazepine, and Metronidazole
  5. What are the dental tx impacts for PPIs?
    • All dec ketoconazole absorption
    • Clarithromycin inc Omeprazole
    • Omeprazole and Rabeprazole inc the 1/2 life of Diazepam and Triazolam
  6. What is an indicator of more severe GI disease?
    • NSAIDS will aggravate GERD
    • PPIs indicate more severe GI disease.
  7. What are PPIs known to inhibit?
    Ca, Mg, and Vit B-12 absorption from food

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