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Osteoporosis
- chronic metabolic disease in which bone loss causes decreased density and possible fracture
- usually silent and often the first sign is hip fracture
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Osteopenia
- a part of osteporosis
- low bone mass
- occurs when osteoclastic activity is greater than osteoblastic activity - bone remodeling is constant
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Primary osteoporosis occurs most often in:
- - women after menopause with decreased estrogen levels
- - thin, lean women of European or Asian descent
- - no exercise
- - diet lacking calcium and vitamin D
- - excessive caffeine intake
- - protein deficiency or excess
- - excessive alcohol or tobacco use
- - excessive exercise
- - anorexia
- - bulimia
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How is osteoporosis classified?
- - generalized/primary = occurs mostly in postmenopausal women and men in their 60s and 70s
- - secondary = results from an associated medical condition (hyperparathyroidism, corticosteroids, long-term immobility)
- - regional = when a limb is immobilized
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Health promotion/illness prevention for osteoporosis
- teaching should begin with young women at 30 years of age
- take vitamin D and calcium
- decrease modifiable risk factors
- avoid sedentary lifestyle
- weight-bearing exercises
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Assessment for osteoporosis
- fall risk
- height and weight
- back pain
- painful joint
- psychosocial
- labs - bone specific alkaline phosphatase; osteocalcin; pyridinium; N-teleopeptide; C-teleopeptide
- DXA - best tool - dual x-ray absorptiometry
- QCT and QUS
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Interventions for osteoporosis
- healthy diet with calcium and vitamin D
- walking 30 minutes 3-5 times a week is the single most effective treatment for prevention
- drug therapy
- surgery - vertebroplasty or kyphoplasty
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Drug therapy for osteoporosis
- supplements (take in divided doses because you only absorb about 500 mg at a time)
- estrogen or hormone therapy (low doses/short duration)
- bisphosphonates (slow bone reabsorption; take on empty stomach with full glass of water first thing in the morning and remain upright for 30 min after taking)
- selective estrogen receptor modulators (mimic estrogen in some parts of the body and block it in other parts)
- calcitonin (decreases bone loss)
- androgens (men)
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Osteomalacia
- loss of bone related to vitamin D deficiency
- bone softens because of inadequate deposits of calcium and phosphorus in the bone matrix
- not common in US
- known as Rickets in children
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Assessment for osteomalacia
- nutrition history
- age
- skin pigmentation
- ability to be exposed to sunlight to build vitamin D
- history of chronic GI distress r/t trouble of absorbing vitamin D
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Treatment for osteomalcia
Vitamin D
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Paget's disease of the bone
- chronic metabolic disorder in which bone is excessively broken down and reformed
- bones are structurally disorganized, weak with increased risk of bowing of long bones and fractures
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Causes of Paget's
- possibly genetic - autosomal dominant inheritance pattern
- could be caused by viral respiratory infection
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Assessment for Paget's
- history of bone fractures
- scoliosis
- kyphosis
- enlarged skull
- predisposed to kidney stones and gout
- diagnostic - increased alkaline phosphatase; radionucleotide bone scan
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Nonsurgical management of Paget's
- analgesics - pain
- decrease bone resorption
- selected bisphosphonates
- calcitonin
- plicamycin (only if they don't respond to other meds)
- diet - increased calcium
- heat
- strength bearing
- massage
- ROM
- relaxation
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Surgical management of Paget's
- tibial osteotomy
- partial or total joint replacement
- decompression and stabilization of spine
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Osteomyelitis
- infection in bony tissue from bacteria/virus/fungi/cut on outside of body/from other area of infection in the body
- very rare in US
- seen more commonly in 3rd world countries
- very hard to treat
- labs
- - high ESR, c-reactive protein, WBC
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Acute osteomyelitis S/S
- fever
- swelling
- erythema
- tenderness in effected area
- localized pain that intensifies with movement
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Chronic osteomyelitis S/S
- skin ulceration
- drainage
- sinus tract formation
- localized pain
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Interventions for osteomyelitis
- antibiotic therapy - IV followed by long course of oral
- hyperbaric oxygen therapy
- sequestrectomy - debride infected bone
- microvascular bone transfers
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Benign bone tumors
often asymptomatic and may be discovered on routine x-rays or as a cause of pathologic fracture - pain is biggest manifestation
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Types of benign bone tumors
- chrondogenic - from cartilage
- osteogenic - from bone
- fibrogenic - from fibrous tissue - most commonly found in children
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Interventions for benign bone tumors
- heat/cold
- analgesics/NSAIDs
- curettage
- joint replacement
- arthrodesis
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Types of bone cancer
- primary tumors - site where cancer starts to grow; affects 10-30 year olds; most common site is distal femur
- metastatic lesions - cancer from one place starts growing in the bone
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Pathophysiology of bone cancer
occurs more often in males and people that had radiation treatment and benign bone lesions, prostate cancer, breast cancer, kidney, thyroid or lung metastasis
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Assessment for bone cancer
- pain
- local swelling
- palpate mass
- treatment aimed at reducing size/removing tumor
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Nonsurgical management of bone cancer
- chemotherapy
- radiation - only palliative if it has metastasized
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Surgical management (post-op care)
- pressure dressing
- wound suction
- hemorrhage risk
- monitor circulation, movement, sensory, infection
- muscle strength, ROM, PT, CPM
- assess psychosocial
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Dupuytren's contracture
- slowly progressive contracture of the palmar fascia resulting in flexion of the fourth or fifth digit of the hand
- very common in European men, families
- can be bilateral
- surgery to release contracture
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Ganglion
- round benign cyst often found on wrist or foot joint/tendon
- usually painless on palpation
- can cause joint discomfort
- rubbing/friction
- sometimes they are aspirated
- tendon sheath deteriorates and becomes weak/distended
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Hallux valgus
- bunion
- more common in women
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Hammertoe
usually 2nd toes
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Morton's neuroma
- plantar digital neuritis
- tumor at end of foot
- needs to be removed
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Tarsal tunnel syndrome
very similar to carpal tunnel syndrome
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Plantar fasciitis
- inflammation of plantar fascia located in arch of foot
- treated with NSAIDs and shoe orthodics
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Scoliosis
- changes in muscles and ligaments on the concave side of the spinal column
- more common in females
- congenital in embryonic development
- screened in middle school/physicals
- sometimes leg lengths will be different
- treatment - bracing, casting, surgery, stabilize the spine (50% of adults)
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