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2011-12-11 15:38:55
nurseing chemo pharm

nursing pharm final
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  1. Insulin, Regular
    Only insulin to be given IV, often Mixed with intermedate or long acting
  2. Insulin lispro, aspart, glulisine
    short duration, rapid acting
  3. insulin NPH, determir
    intermediate duration
  4. insulin ultralente
    long duration
  5. Hypoglycemia
    Ealy, weakness hunger, tachycardia, cool skin, trembling; later HA, blurred vision, incoherent speech
  6. hyperlglycemia
    Drowsiness, flushed dry skin, fruity breath, frequent urination, lost of apatite, excessive thirst
  7. Biguanides: Metformin (Glucophage)
    decreases hepatic gluscose production, increases uptake, does NOT stimulate insulin release. Needs renal and liver funtion tests, ***Cimetidine increases DM by 60%
  8. Sulfonureas: Tolbutamide, Glipizide, Glyburide Glimpride
    Stimulate relase of insulin from pancrease ***avoid while pregnant avoid ETOH***
  9. Meglitinides: Repaglinide, Nateglinide
    stimlate relse of insulin (work best with A1c<8/5), 30min before meal, safe on renal and liver ***Antifungals and macrolides increase levels of repaglinide**Gemfibrozil and repglinide may lead to hypoglycemia
  10. Thiazolidinedions: Rosiglitazone, Pioglitazone
  11. Alpha-Glucosidase inhibitor, Acarbose
    inhibits absorbson of glucose, TID after first bit of meal ***interacts Charcole, Digoxin, Propranolol, Ranitidine***
  12. Pramlinitide
    contorls postprandial hyperglycemia by slowing gastric emptying SQ 15min before meals
  13. Exenatide
    SQ 60min AC promotes insulin secretion, may decrease absorption of PO drugs
  14. Liraglutide
    increases insulin relase when glucose is high
  15. Levothyroxine
    Artafical thyroid
  16. Propylthiouracil
    inhibits synthesis of thyroid
  17. Sodium iodide
    distroys thyroid gland
  18. Growth hormone: somatotropin
    stimulates liner growth, very expensive
  19. antidiuretic hormone
    no ADH=diabetis insipidus
  20. vasopressin (Pitressin)
  21. Desmopressin
    drug of chose for treatment of diabitus insibidus]
  22. hydrocortisone
    short acting glucocorticoid
  23. prednisone, Methylprednisone
    intermediate acting gucocorticoid
  24. dexamethasone
    long acting glucocorticoid
  25. Fludocortisone
    mineralcorticoid affect water and electrolyte imbalnce
  26. Magnesium sulfate
    pregnancy seizure prophylaxis relaxes smooth muscle
  27. Ritodrine, Terbutaine
    treat preterm labor
  28. Sildenafil viagra
    do not se with nitrates
  29. Finasteride Flowmax
    treats BPH, Finasteride also treats alopecia
  30. Filgrastim (Neupogen)
    elevates neutrophil
  31. Oprelvekin (Neumega)
    stimulates platelets
  32. Epoetin alpha (erythropoietin)
    istimulates RBC, PALLIATIVE ONLY
  33. ondanzetron (Zofran) Aprepitant (Emend)
    antiemetic often given with dexamethasone
  34. Allopurinol (Syloprim)
    used to treat Chemo Alopecia & Tumor lysis syndrom
  35. Tumor Lysis syndrom
    increased uric acid, K+, Ca+, P+
  36. Cyclophosphamide, Ifosfamide
    cytotoxic can cause Hemmoragic cysitis
  37. carmustine (BCMU)
    cytotoxic agent, croses blod brain barrior
  38. Cisplatin
    Cytotoxic (Pt compound) renal and ototoxic
  39. carboplatin
    hard on platelets
  40. Oxalipatin
    cold induced neuropothy
  41. Methotrexate (Rheumatrex)
    used with Leucovin (rescue drug)
  42. Fluorouracil (5FU)
    used for solid tumor, cell cycle specific
  43. DOXOrubicon (Adriamycin
    causes red urine, can be used with Dexrazoxane to reduce cardiotoxicity
  44. Paclitaxel, Docetaxel
    taxane mitotic inhibitor, cuases anaphalaxys, pheripral neuropathy, alopecia
  45. Etoposide (VePesid)
    mitotic iinhibitor can cause orthostatic hypotension
  46. Leuprolide, Flutamide, Estrogins
    used for prostate cancer
  47. Raloxifene,tamoxifen
    Selective estrogin receptor modulators, Raloxifen has been aproved for osteoprosis
  48. Megestrol acetate (Megace)
    used for endometrial & brest CA, also treats CA & AIDS anorexia
  49. Trastuzumab (Herceptin)
    brest cancer biological response modifier
  50. Bevacizumab (Avastin)
    angiogenesis inhibitor
  51. CycloSPORINE, Tacrolimus, Azathioprine
    immunosupressant used for transplant
  52. Rho immune globulin
    supress antibody response of RH- woman, given at 28wks and 72hr after birth