Carbohydrate Metabolism (Grogan)

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Author:
catitasilva
ID:
122860
Filename:
Carbohydrate Metabolism (Grogan)
Updated:
2011-12-11 20:03:59
Tags:
Carbohydrate Metabolism Grogan
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Carbohydrate Metabolism (Grogan)
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  1. Glycogen Synthesis:
    What are the 3 bypass steps
    • 1. OAA + ATP --> PEP (PEPcarboxykinase)
    • 2. F1,6BP --> F6P (F6Phosphatase)
    • 3. G6P --> Glucose (G6Phosphatase)
  2. Name the pathway & disorder
    Glucose --> Ribose
    • Pentose Phosphate Pathway (PPP)
    • G6PDH deficiency - RBC hemolysis
  3. Name the pathway & associated disorder:
    Fructose --> Pyruvate
    • Fructose Metabolism
    • Fructokinase Deficiency: essential fructosoria
    • Aldolase B Deficiency: fructose intolerance
  4. Name the pathway & associated disorder:
    Galactose --> Glucose
    • Galactose Metabolism
    • GalPUT deficiancy: cataracts, retarded & cirrhosis
  5. Von Gierke's (Ia & Ib)
    • G6Pase or glucose transporter deficiency
    • Tx: steady carb diet
  6. Mc Ardle's (V)
    • muscle phosphorylase deficiency
    • muscle cramps w/exercise
    • Mb & CK in blood
  7. Pompe's (II)
    • lysosomal acid glucosidase deficiency
    • heart failure in infants --> death

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