Nicotine stimulates cholinergic receptors of the autonomic nervous system. Based on this information, how would cigarette smoking affect the CV system?
Cholineric receptors are found in all ganglia of the ANS, so nicotine would stimulate both sympathetic and parasympathetic responses in CV tissues. Although increased sympathetic stimulation increases heart rate and force of contration, increased parasympathetic stimulation simultaneously decreases blood flow to the heart muscle. In addition to elevating heart rate and force of contraction, sympathetic stimulation also constricts peripheral VS, all which INCREASE BP