Self Care- Psoriasis Treatments and Approaches

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Author:
mwill222
ID:
123946
Filename:
Self Care- Psoriasis Treatments and Approaches
Updated:
2011-12-15 17:49:12
Tags:
pharmacy
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Description:
Fall 2011 PT Module III: Psoriasis
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  1. What are the other treamtent options for psoriasis?
    • balneotherapy
    • tacrolimus
    • pimecrolimus
    • mycopehnolate mofetil
    • sulfasalazine
    • 6-Thioguanine
    • hydroxyurea
    • azathioprine
    • leflunomide
  2. What is balneotherapy?
    • exposure to sea salt
    • daily sunbathing
  3. What is tacrolimus?
    immunosuppressive agent taken PO for recalcitrant plaque-type psoriasis
  4. What is pimecrolimus?
    immunosuprresive agent for atopic dermatitis dosed topically BID
  5. What is mycophenolate mofetil?
    anti-rejection medication dosed orally QID
  6. What is sulfasalazine?
    • used in IBS, RA dosed orally
    • less effective than MTX, PUVA, or acitretin
  7. What is 6-thioguanine?
    antimetabolite used in leukemia dosed twice a week with less hepatic toxicity than MTX
  8. What is hydroxyurea?
    antimetabolite for various malignancies dosed orally per day that has less hepatic toxicity and less effective than MTX
  9. What is azathioprine?
    • a purine antimetabolite indicated to prevent rejection of renal transplant
    • dosed 75-150 mg PO daily
  10. What is leflunomide?
    • a pyrimidine synthesis inhibitor for RA
    • dosed 20 mg PO daily after 100 mg daily x3 days load
  11. What are the goals of psoriasis therapy?
    • reduce or clear signs
    • increase QOL
  12. What determines PASI?
    • BSA involved
    • degree of erythema, induration, and scaling
  13. What 4 sections is the body broken down into to determine PASI?
    • head
    • arms
    • trunk
    • legs
  14. What is the range of PASI?
    0-72
  15. What % reduction is usually significant in clincial trials when monitoring disease severity?
    50%
  16. What are the PASI values for mild, moderate, and severe psoriasis?
    • mild <12
    • mod 12-18
    • severe >18
  17. What needs to be taken into consideration when developing a treatment plan?
    • extent and site of disease involvement
    • age
    • concurrent diseases
    • mild-mod <20% BSA
    • severe >20%
  18. What are the treatment options for psoriasis on the scalp?
    topical steroid, calcipotriene solution, coal tar shampoo
  19. What are the treatment options for psoriasis in nails?
    • topical steroid under nail
    • systemic therapy
  20. What are the treatment options for psoriasis on genitalia?
    • low-potent corticosteroid lotion
    • topical calcipotriene
  21. What are the treatment options for psoriasis on the palms and soles?
    • high-potent steroid
    • MTX
    • or acitretin
  22. What areas are ointments used for?
    • hands
    • feet
    • trunk
    • places with little hair
  23. What areas are creams used for?
    • facial
    • axilla
    • groin
    • smooth or hairy skin
  24. What areas are gels used for?
    • hairy areas
    • scalp
  25. What areas are lotions used for?
    • face
    • scalp
    • axilla
    • groin
    • ear canal
  26. What are condsidered 1st line therapies for vulgaris?
    • topical steroids
    • calcipotriene
    • UVB
  27. What are considered 1st line therapies for guttate?
    • topical steroids
    • UVB
  28. What are considered 1st line therapies for erythrodermic?
    • systemic retinoids
    • immunomodulatory agents
    • MTX
    • cyclosporine
  29. What are considered 1st line therapies for pustular?
    • coal tar
    • systemic retinoids
    • immunomodulatory agents
    • MTX
    • cyclosporine
  30. What are considered 1st line therapies for arthritis?
    • NSAID +/- immunomodulatory agents
    • MTX

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