PACOP 1-- Phy. Pharm.

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PACOP 1-- Phy. Pharm.
2012-01-12 04:14:09

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  1. The buffer equation is also known as:
  2. The dissolution of a drug is calculated using:
  3. The vaopr pressure of a solution is ___ by the presence of a solute.
  4. To increase the miscibility of partially miscible liquids, add substance,
    miscble with both liquids
  5. The number of moles of solute per liter of solution;
  6. The number of gram equivalents of solute per liter of solution:
  7. The number of moles of solute per 1000g of solvent :
  8. Crystalline form of NaCl:
  9. A type of solution where the dispersed phase is uniform throughout the solution:
    true solution
  10. Diffusion mechanism whereby drugs are transported from a region of high to low concentration:
  11. Diffusion mechanism whereby drugs are transported from a region of low to high concentration:
  12. An equation which reveals the rate of diffusion of a drug:
    Fick's first law
  13. The ff statements are true for dustibility, except
    1. it signifies the opposite of stickiness
    2. it charaacterizes the free-flowing powders
    3. it has some relation to the uniform spreading of dusting powders when applied to the skin
    4. it is a measure of the cohesiveness of particles of a compacted powder
  14. Complete wetting of a surface occurs when the contact angle between a liquid droplet & the surface is:
  15. Gels & magmas when standing form semisolids & on shaking become fluid are said to be:
  16. The attractive forces between polar molecules, that is, between molecules that possess dipole movement:
    Keesom Forces
  17. The existence of elemental sbstances such as carbon & sulfur, in more than one crystalline form:
  18. A method meaasuring tonicity which is based on the effect of various solutions of the drugs observed on the appearance of RBCs suspending in the solutions:
    Hemolytic method
  19. The effect of pressure on the solubility of a gas is expressed by ___, which states that in every dilute solution at constant temperature, the concentration of dissolved gas is proportional to the partial pressure of the gas above the solution at equilibrium:
    Raoult's Law
  20. The attractive interaction between a polar molecule & the induces dipole:
    Dipole-Induced Dipole interaction
  21. The following are not actionic surfactants, except:
    1. Potasiium Laureate
    2. Quaternary NH4 compounds
    3. Na Lauryl Sulfate
    4. Triethanolamine Stearate
  22. The bulk density of a powder depends primarily on the following, except:
    1. particle size distribution
    2. particle sedimentation
    3. particle shape
    4. tendency of the particles to adhere to one another
  23. When the stress is removed, a___ systems returns to its original states of fuidity
  24. An example of liquid-liquid interface:
    1. Emulsion
    2. Suspension
    3. Mixture
    4, Gels
  25. The degree of adsorption of a gas by a solid depends on the :
    1. chemical nature of the adsorbent
    2. surface area of adsorbent
    3. tempearature
  26. The following are methods of determining particle size, except:
    1. sedimentation
    2. optical microscopy
    3. density
    4. particle volume measurement
  27. The ratio of the void volume to the bulk volume of the packing:
  28. Type of particle density which is determined by the displacement of mercury:
    granule density
  29. Kinematic viscosity is also known as:
    absolute viscosity
  30. Viscosity of a pseudoplastic substance decreases with increasing ____:
    shearing stress
  31. As the temperature increases, the solubility of most gases decreases, owing to the greater tendency of the gas to ____
  32. The ff are not organic molecular complexes, except:
    1. Clathrates
    2. Picric acid type
    3. Channel Lattice type
    4. Olefin type
  33. The ff are methods of determining the type of emulsions, except:
    1. dye method
    2. conductivity test method
    3. cryoscopic method
    4. dilution test method
  34. The change of emulsion type from O/W to W/O or vice versa is known as:
    phase inversion
  35. Relatively insoluble:
    1. less than 1 part solute
    2. 100-1000 parts solvent
    3. more than 10,000 parts of the sovent
    4. less than 10,000 parts of the solvent
  36. The ff are hydrophilic substituents, except:
    1. alkyl group
    2. amino group
    3. hydroxyl group
    4. carbonyl group
  37. Molecular weight & mass are examples of ___ property:
  38. Water is a ___ liquid:
    1. newtonian
    2. plastic
    3. pseudoplastic
    4. dilatant
    5. thixotropic
  39. Proposed law of summation:
    Hess law
  40. As the length of a non-polar chain of an aliphatic alcohol increases, the solubility of compound water;
  41. Type of reaction wherein the rate is independent of the concentration of reactants termed as :
    zero order reaction
  42. The fastest order of reaction to decompose, since according to its differential rate expression, it is independent of the remaining concentration of the drug after decomposition:
  43. This type of solution has a solute concentration equivalent to its limit of solubility. This would mean that if the same solute is added to this solution, even in minute amounts, will lead to crystallization, precipitation or insolubility of the solute:
    saturated solution
  44. Example of constitutive property:
    1. mass
    2. molecular weight
    3. optical activity
    4. temperature
  45. The increase in mutual solubility of 2 partially miscible solvent by another agent is referred to as:
  46. Number of moles perkilogram solvent:
  47. One of these exhibit dilatant flow:
    1. cream
    2. ointment
    3. paint
    4. acacia mucilage
  48. Which of the ff is true:
    1. solubility increases with increased particle size
    2. solubility increases with decreased particle size
    3. solubility decreases with increased particle size
    4. solubility decreases with decreased particle size
  49. Ascorbic acid is the least stable of all vitamins. Its instability is via this reaction:
  50. This method of determining the overall order of reaction involves the use of different plots. The plot will form a straight line that will determine the order:
    graphical method
  51. If one gram of solute dissolves in 30-100 parts of solvent, the solute is said to be ___ in that solvent:
    sparingly soluble
  52. Method of adjusting the tonicity of solution to conform that of the blood & lacrimal fluid based on the adjustment of the freezing point of the solution to -0.52oC
    Cryoscopic method
  53. Method of adjusting the tonicity of solution to conform that of the blood & lacrimal fluid based on the adjustment of the freezing point of the solution to 0.9 NaCl:
    Cryoscopic method
  54. Method of adjusting the tonicity of a solution to conform that of the blood & lacrimal fluid based on the used of the calculated volume V values when the weight of the drug is 0.3 g, followed by the dilution of this solution with an already isotonic, usually buffered solution to the appropriate volume
    Sprowls method
  55. Equation showing the buffer capacity of a solution: