Kullgren

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Author:
jaguavai
ID:
127466
Filename:
Kullgren
Updated:
2012-01-12 16:56:54
Tags:
Pharm 421 opoids anesthesia etc
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Description:
Pharm 421 and so CVS intro
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  1. Agonizing Mu receptor produces
    Euphoria! Remember this one
  2. Pentazocine, nalbuphine, butorphanol
    • Mu antagonist
    • Kappa agonist
  3. Buprenorphine
    • Mu partial agonist
    • Kappa antagonist
  4. Phenanthrenes (6)
    • Morphine
    • Codeine
    • Hydromorphone
    • Hydrocodone
    • Oxycodone
    • Oxymorphone
  5. Diphenylheptane derivatives
    • Methadone
    • Propoxyphene
  6. Phenylpiperidine derivatives
    • Meperidine
    • Fentanyl
  7. CNS side effects of opoids (3)
    • Miosis
    • N/V
    • Cough suppression
  8. Peripheral opoid side effects (3)
    • Urinary retention
    • Biliary spasm
    • Orthostatic hypotension
  9. Opoids caution in renal failure (2)
    • morphine
    • hydromorphone
    • (caution in renal defficiency)
  10. Opoinds that require metabolism (7)
    • Codeine
    • Morphine
    • Hydrocodone
    • Hydromorphone
    • Oxycodone
    • Fentanyl
    • Methadone
  11. Opoid agonist/antagonist (4)
    • Pentazocine
    • Buprenorphine
    • Butorphanol
    • Nalbuphine
  12. Opoid antagonists (4)
    • Naloxone
    • Naltrexone
    • Nalmefene
    • Methylnaltrexone
  13. Opoid-related for diarrhea (2)
    • Diphenoxylate w/atropine
    • Loperamide (max 16mg)
  14. Alterations in Alzheimer's disease (4)
    • Cortical atrophy (brain shrinks)
    • Degeneration of cholinergic neurons
    • Presence of neurofibrillary tangles
    • Neuritic plaques
  15. Targets for AD drugs (2)
    • Lack of acetylcholine
    • Too much glutamate
  16. AChE Inhibitors (3)
    • Donepezil
    • Rivastigmine
    • Galantamine
  17. Stages of Anesthesia (4)
    • Induction
    • Excitement
    • Surgical Anesthesia
    • Impending death/overdose
  18. Dissociative Anesthetics (2)
    • PCP
    • Ketamine
  19. Opoids in anesthesia (4)
    • Fentanyl
    • Alfentanil
    • Sufentanil
    • Ramifentanil
  20. Halogenated hydrocarbons (6)
    • Halothane
    • Methoxyflurane
    • Enflurane
    • Isoflurane
    • Desflurane
    • Sevoflurane
  21. Adjunct agents (4)
    • Alpha 2 agonists
    • Benzos
    • Analgesics
    • Neuromuscular blocking agents
  22. Local anesthetics loss of sensation (5 in order)
    • 1 - Pain
    • 2 - Cold
    • 3 - Warmth
    • 4 - Touch
    • 5 - Pressure
  23. LA Esters (4)
    • Tetracaine
    • Procaine
    • Cocaine
    • Benzocaine
  24. LA Amides (5)
    • Bupivacaine
    • Ropivacaine
    • Lidocaine
    • Mepivacaine
    • Prilocaine
  25. Preload
    Tension exerted by blood on chamber wall before systole
  26. Afterload
    • Tension developed in the chamber wall to pump blood out, determined by peripheral resistance
    • Contractile force
  27. Frank-Starling Law
    Contractile forse is directly proportional to preload (more blood in ventricle = more forceful contraction)
  28. SA node is
    pacemaker
  29. AV node slows
    the signal down
  30. L type Ca channels are on
    the heart

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