DIT Day 1

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pszurnicki
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127826
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DIT Day 1
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2012-01-16 20:26:01
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DIT Day
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DIT Day 1
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  1. What congenital anomalies do the following produce?
    1. ACEI
    2. ETOH
    3.Alkylating Agents
    4. Aminoglycosides
    5. Cocaine
    6. DES
    7. Folate antagonist/valproate
    8.Valproate
    9.Iodine
    10. Lithium
    11.Maternal Diabetes
    12.Smoking, Nicotine, CO
    13. Tetracycline
    14. Thalidomide
    15. Vitamin A excess
    16. Warfarin
    • ACEI-renal Damage
    • ETOH-FAS, MR, microcephaly
    • Alkylating Agents--missing digits
    • Aminoglycosides- CN 8
    • Cocaine- Placental abruption, ischemia--preecclampsia
    • DES--Vaginal Clear cell Adenocarcinoma
    • Folate Antagonist/Valproate--NTD
    • Iodine-congenital goiter or hypothyrodism
    • Lithium-Ebstein's abnormality atrialized ventricle
    • Maternal DM-TOGV, hypoglycemia, macrosomia, anal atresia
    • Smoking, nicotine, CO--ADHD, IUGR, placental ischemia
    • Tetracycline-Discolored Teeth
    • Thalidomide-absence of limbs
    • Vitamin A excess- cleft palate,spontaneous abortion
    • Warfarin--Bone Deformity and fetal hemorrhage
  2. ?Symptoms of Ankylosing spondylitis?
    • sacroilliatis
    • uveitis
    • aortitis
    • costovertebral joint inflammation--hypoventilation
  3. What are the 5 enzymes involved in heme synthesis?
    • ALA synthase--Heme/Glucose/Lead inhibit/\Etoh, benzo, hypoxia stimulates
    • ALA dehydratase
    • porphobilinogen deaminase
    • Uroporphobilinogen Decarboxylase
    • Ferrochelatase-lead inhibits
  4. 3 places for Vit B6 pyridoxine?
    • heme synthesis
    • INH
    • peripheral dopa decarboxylase
  5. In a positive skewed distribution where is the mean?
    in a negatively skewed distribution where is the mean?
    • to the left
    • to the right
  6. What kind of gastric anomaly is present in Pataus? vs downs?
    • Patau--pyloric stenosis/omphalocele
    • Downs---duodenal atresia/Hirshsprung
  7. Syndrome with prolonged QT interval and sensory neural hearing loss?
    Jervel-Lange Nielsen Syndrome
  8. 4 Second generation of H1 blockers?
    3 1st generation of H1 blockers?
    • 2nd Generation:
    • Loratadine
    • Fexofenadine
    • cetrizine
    • desloratadine
    • 1st generation:
    • Diphenhydramine
    • Dimenhydraminate
    • Chlorpheniramine
  9. 4 Drugs with low TI?
    • Lithium
    • Phenobarbital
    • Warfarin
    • Digoxin
  10. What are the 3 enzymes involved in the synthesis of hypochlorite?
    • NADPH oxidase
    • SOD
    • Myeloperoxidase
  11. What 2 conditions give strawberry tongue?
    • Scarlet Fever
    • Kawasaki
  12. 2 skin infections caused by both staph aureus and s. pyogens?
    • cellulitis
    • folliculitis
    • impetigo
  13. TNF alpha inhibitirs i.e Infliximab, adulimumab, etanercept predispose to what?
    Tb
  14. What pneumoconiosis predisposes to Tb?
    Silicosis
  15. What is an axonal reaction?
    • regeneration of axon following a severance
    • you see
    • swelling of the axonal body
    • peripheral displacement of nucleus and nissl bodies
  16. Inner restleness and inability to sit still see in with conjuction with anti-psychotic meds is called?
    akathisia
  17. 2 Effects of using Beta blockers for Hypertension?
    decreases contractility and decreased renin production so it will decrease alpha one effects on the blood vessels
  18. Squamous epithelium is found in what part of the respiratory tract?
    true vocal chords
  19. Drugs used for Restless leg syndrome?
    • Parkinsons's
    • levidopa/carbidopa
    • Pergolide
    • Bromocriptine
  20. Dopamine agonists for Parkinsons?
    • pramipexole
    • repirinole
    • Bromocriptine
    • Pergolide
  21. What nucleus controls circadian rhythm?
    Suprachiasmatic nucleus--NE---Pineal Gland---Melatonin

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