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Mechanism of Action;
Increases electrical stimulation threshold of ventricle, His-Purkinje system by affecting sodium channels, which stabilizes cardiac membrane, decreases automaticity
Ventricular tachycardia, ventricular fibrillation, cardiac arrest
Contraindications & Precautions;
Contraindications; hypersensitivity, heart blocks, supraventricular dysrhythmias, bradycardia with PVCs, systolic < 90 mmHg systolic · Precautions; hepatic disease, CHF, respiratory depression, elderly ·
Route and Dosage;
IV, 1-1.5 mg/kg q 5-8 min, max dose 3 mg/kg; Peds 1mg/kg
NOTE bolus dose of lidocaine lasts approx. 20 min. administer lidocaine gtt to maintain desired levels once arrhythmia is corrected or spontaneous circulation returns. Add 1 gm lidocaine to 250 cc of NS (concentration of 4 mg/ml); gtt at 1-4 mg/min.
Adverse reactions and side effects;
heart block, respiratory depression, seizures, hypotension
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